Large helical conformational deviations from ideal B-DNA and prokaryotic regulatory sites.
Large helical conformational deviations from ideal B-DNA and prokaryotic regulatory sites.
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与理想的 B-DNA 和原核调节位点存在较大的螺旋构象偏差。
DOI：
10.1016/s0022-5193(85)80094-1
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发表时间：
1985
影响因子：
2
通讯作者：
Ruth Nussinov
中科院分区：
文献类型：
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作者：
Ruth Nussinov
沿着大约60个细菌和噬菌体序列，每个几百个核苷酸长，计算了几个双螺旋DNA角参数的变化。在调节蛋白识别位点或其附近发现了大的几何不规则区域。基于这些广泛的计算，我认为这些结构上的“皱纹”区域促进了识别过程的第一阶段。
The variations in several double helical DNA angular parameters have been calculated along about 60 bacterial and phage sequences, each several hundreds nucleotides long. Regions of large geometric irregularities are found at, or in the vicinity of, regulatory protein recognition sites. Based on these extensive computations I suggest that these structurally" wrinkled" regions facilitate the first stage of the recognition process.
肠杆菌科脂蛋白基因的比较。
DOI：
--
发表时间：
1981
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Yamagata,H;Nakamura,K;Inouye,M
通讯作者：
Inouye,M