Test-retest reliability of the 40 Hz EEG auditory steady-state response.

Test-retest reliability of the 40 Hz EEG auditory steady-state response.
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DOI:
10.1371/journal.pone.0085748
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Rojas DC
Rojas DC
中科院分区:
综合性期刊3区
文献类型:
--
作者:
McFadden KL;Steinmetz SE;Carroll AM;Simon ST;Wallace A;Rojas DC

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听觉诱发的稳态反应越来越多地被用作各种神经精神疾病的脑功能和功能障碍的标志,但缺乏对这种反应的测试-重测可靠性的研究。本研究的目的是评估听觉稳态反应(ASSR)的一致性。此外,本研究旨在探讨刺激参数和分析方法对ASSR信度的影响。在19名健康成人中,使用脑电图(EEG)测量了间隔约1周的两次治疗期间这种反应的一致性。ASSR同时受到40 Hz调幅白噪声和咔嚓列车刺激。会话之间的相关性通过两种单独的分析技术进行评估:a)整个头部阵列的通道级分析和b)听觉偶极子的信号空间投影。总体而言,ASSR在第一阶段和第二阶段之间显著相关(p<0.05,多重比较校正),表明该反应具有足够的重测信度。目前的研究还表明,试验阶段间一致性的测量可能比诱发能力的测量更可靠。两种分析方法之间的结果相似,但可靠性因所呈现的刺激而异,滴答列车刺激产生的反应比白噪声刺激更一致。
Auditory evoked steady-state responses are increasingly being used as a marker of brain function and dysfunction in various neuropsychiatric disorders, but research investigating the test-retest reliability of this response is lacking. The purpose of this study was to assess the consistency of the auditory steady-state response (ASSR) across sessions. Furthermore, the current study aimed to investigate how the reliability of the ASSR is impacted by stimulus parameters and analysis method employed. The consistency of this response across two sessions spaced approximately 1 week apart was measured in nineteen healthy adults using electroencephalography (EEG). The ASSR was entrained by both 40 Hz amplitude-modulated white noise and click train stimuli. Correlations between sessions were assessed with two separate analytical techniques: a) channel-level analysis across the whole-head array and b) signal-space projection from auditory dipoles. Overall, the ASSR was significantly correlated between sessions 1 and 2 (p<0.05, multiple comparison corrected), suggesting adequate test-retest reliability of this response. The current study also suggests that measures of inter-trial phase coherence may be more reliable between sessions than measures of evoked power. Results were similar between the two analysis methods, but reliability varied depending on the presented stimulus, with click train stimuli producing more consistent responses than white noise stimuli.
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