Testicular cancer in the United States: trends in incidence and mortality.

Testicular cancer in the United States: trends in incidence and mortality.
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美国睾丸癌:发病率和死亡率的趋势。

DOI:
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发表时间:
1986
影响因子:
7.7
通讯作者:
J. Flannery
J. Flannery
中科院分区:
医学1区
文献类型:
--
作者:
L. Brown;L. Pottern;R. Hoover;S. Devesa;P. Aselton;J. Flannery

文献摘要

被引文献

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在美国睾丸癌的发病率和死亡率的模式表明,年龄,种族,时间段和地理区域的实质性差异。随着时间的推移,15至44岁的年轻男子患睾丸癌的风险普遍增加,最近出生的同龄人的增加率最高。事实上,一些证据表明,有可能出现两次独立的增长,一次是从20世纪30年代末到50年代末,第二次出现在20世纪70年代末。黑人的发病率数据也显示了一个年轻的成年人高峰,尽管白人的发病率在所有年龄段(幼儿期除外)都比黑人高出四到五倍。老年男子的死亡率在30年期间持续下降,而年轻男子的死亡率只是在最近一段时间才出现大幅下降。尚未确定的病因因素可能是年轻人睾丸癌发病率增加的原因。生存因素似乎可以解释发病率和死亡率曲线随时间变化的年龄特异性差异。
The patterns of incidence and mortality of testicular cancer in the United States indicate substantial differences by age, race, time period, and geographical region. An epidemic increase over time in the risk of testicular cancer is noted for young men aged 15-44, with the most recent birth cohorts showing the greatest rate of increase. Indeed, some of the evidence suggests the possibility of two separate increases, one apparent from at least the late 1930's through the late 1950's and the second appearing in the late 1970's. The incidence data for blacks also show a young adult peak, even though the rates for whites are four to five times higher than for blacks at all ages except early childhood. Mortality rates for older men consistently declined over the 30-year period, while rates for younger men showed a dramatic drop only for the most recent time period. Aetiological factors yet to be determined may be responsible for the increasing incidence of testicular cancer in young adults. Survival factors appear to explain the age-specific differences between the incidence and mortality curves over time.