Sensitivity encoding for diffusion-weighted MR Imaging at 3.0 T: intraindividual comparative study
Sensitivity encoding for diffusion-weighted MR Imaging at 3.0 T: intraindividual comparative study
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DOI：
10.1148/radiol.2342031626
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发表时间：
2005-02-01
期刊：
影响因子：
19.7
通讯作者：
Schild, HH
中科院分区：
文献类型：
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作者：
Kuhl, CK;Gieseke, J;Schild, HH
目得：前瞻性评价与常规相位编码的弥散加权（DW）磁共振（MR）成像相比，3.0 T下采用灵敏度编码（SENSE）的DW MR成像是否有助于提高患者缺血性病变的图像质量、诊断信心和准确性。材料和方法：患者在解释研究后提供知情同意书，机构审查委员会批准了研究方案。85例患者（46例男性和39例女性患者;年龄范围：13-86岁;平均年龄：52岁）在3.0 T下接受了两次单次激发自旋回波回波平面DW MR成像，随机顺序：一次采用传统相位编码（重复时间毫秒/回波时间毫秒，4283/79），一次采用SENSE（3141/69，缩减因子为3）。对于这两种情况，使用128 x 128矩阵，24个4 mm厚的切片，以及0和1000 sec/mm（2）的两个B值。使用了一个八元件SENSE兼容的仅接收表面线圈;内置体线圈用于射频传输和生成线圈灵敏度曲线。比较SENSE和传统相位编码的图像质量、信噪比、相对信号强度（SI）和病变对比度。两名神经放射科医生阅读图像。比较常规相位编码和SENSE在MR成像中检测表观扩散系数（ADC）病变的诊断准确性和置信度;配对Wilcoxon符号秩检验用于检验统计显著性。在使用SENSE进行MR成像时，由于图像失真和模糊的大幅减少，因此获得了一致且显著（P < .001）的较高图像质量评分。两种技术的病变对比度等同。使用SENSE进行MR成像时，显示和排除病变的诊断信心显着更高（P < .001）。在3例患者中，小微栓塞病变仅在SENSE MR成像中被前瞻性诊断，而它们被相邻的敏感性效应所掩盖，因此在常规相位编码MR成像中被忽略。结论：SENSE并行MR成像在3.0 T下是可行的。它显著提高了图像质量，特别是通过减少甚至防止易磁化引起的SI变化和图像模糊。有一个显着提高的诊断信心与ADC的变化被确定或排除。(C)RSNA，2005年。
PURPOSE: To prospectively evaluate whether diffusion-weighted (DW) magnetic resonance (MR) imaging with sensitivity encoding (SENSE) at 3.0 T can help to improve image quality and confidence in and accuracy of diagnosis of ischemic lesions, compared with DW MR imaging with conventional phase encoding, in patients.MATERIALS AND METHODS: Patients provided informed consent after the study had been explained, and the institutional review board approved the study protocol. Eighty-five patients (46 male and 39 female patients; age range, 13-86 years; mean age, 52 years) underwent single-shot spin-echo echo-planar DW MR imaging at 3.0 T twice, in a randomized order: once with conventional phase encoding (repetition time msec/echo time msec, 4283/79) and once with SENSE (3141/69, with a reduction factor of three). With both, 128 x 128 matrix, 24 4-mm-thick sections, and two b values of 0 and 1000 sec/mm(2) were used. An eight-element SENSE-compatible receive-only surface coil was used; the built-in body coil served for radiofrequency transmission and generation of the coil sensitivity profile. SENSE and conventional phase encoding were compared for image quality, signal-to-noise ratio, relative signal intensity (SI), and lesion contrast. Two neuroradiologists read images. Diagnostic accuracy of and confidence in detection of apparent diffusion coefficient (ADC) lesions with conventional phase encoding and SENSE at MR imaging were compared; matched-pairs Wilcoxon signed rank test was used to test statistical significance.RESULTS: No major SENSE-related artifacts were seen. At MR imaging with SENSE, consistently and significantly (P < .001) higher image quality scores were achieved because of substantial reduction of image distortions and blurring. Lesion contrast was equivalent with both techniques. Diagnostic confidence for demonstration and exclusion of lesions was significantly (P < .001) higher at MR imaging with SENSE. In three patients, small microembolic lesions were only prospectively diagnosed at MR imaging with SENSE, whereas they were masked by adjacent susceptibility effects and therefore overlooked at MR imaging with conventional phase encoding.CONCLUSION: Parallel MR imaging with SENSE is feasible at 3.0 T. It significantly improves image quality, particularly by reducing or even preventing susceptibility-induced SI changes and image blurring. There was a significantly improved diagnostic confidence with which ADC changes were identified or excluded. (C) RSNA, 2005.