Lessons learned from poisoning cases caused by 2 illegal rodenticides: Tetramine and fluoroacetamide.
Lessons learned from poisoning cases caused by 2 illegal rodenticides: Tetramine and fluoroacetamide.
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毒鼠强和氟乙酰胺两种非法灭鼠剂中毒事件的教训
DOI：
10.1097/md.0000000000005103
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发表时间：
2016-10
期刊：
影响因子：
1.6
通讯作者：
Liu L
中科院分区：
文献类型：
--
作者：
Wang R;Zhuo L;Wang Y;Ren L;Liu Q;Liu L
毒鼠强（tetramethyldisulphotetramine，TETS）和氟乙酰胺（fluoroacetamide，FAA）是一种对动物和人类具有高毒性的非法灭鼠剂，可导致严重的临床症状，包括意识减退、惊厥、昏迷甚至死亡。本文报告2例鼠药中毒病例。尽管患者表现严重，但最初被误诊，最终导致2人死于TETS和FAA中毒。从这2例的临床和法医学经验，我们建议，医生应考虑TETS和FAA中毒时，患者出现全身性癫痫发作，特别是在一些情况下，没有明确的原因和诊断的疾病。早期诊断和治疗是积极处理和刑事调查故意中毒案件的关键。加强临床毒理学教育。
Tetramine (tetramethylene disulphotetramine, TETS) and fluoroacetamide (FAA) are known as illegal rodenticides with high toxicity to animal species and human beings, which could lead to severe clinical features, including reduction of consciousness, convulsions, coma, and even death. We presented 2 cases that involved rodenticides poisoning. Even though the patients showed severe manifestations, they were initially misdiagnosed, resulting in 2 persons finally died from TETS and FAA poisoning in homicide cases. From the clinical and forensic experience of these 2 cases, we suggest that physicians should consider TETS and FAA poisoning when patients present generalized seizures, especially in some cases without clear cause and diagnosis of disease. Early diagnosis and treatment are essential for positive management and criminal investigation in intentional poisoning cases. Moreover, clinical toxicology education should be reinforced.