Silver(I) triflate-catalyzed direct synthesis of N-PMP protected α-aminopropargylphosphonates from terminal alkynes
Silver(I) triflate-catalyzed direct synthesis of N-PMP protected α-aminopropargylphosphonates from terminal alkynes
复制标题
DOI：
10.1021/ol0627810
复制
发表时间：
2007-01-04
期刊：
影响因子：
5.2
通讯作者：
Zhao, Cong-Gui
中科院分区：
文献类型：
--
作者：
Dodda, Rajasekhar;Zhao, Cong-Gui
采用三氟甲磺酸银（I）催化的一锅法三组分反应合成了N-PMP保护的α-氨基炔丙基膦酸酯。用一个非常简单的方法就可以得到好到极好的所需产物的产率。
N-PMP protected alpha-aminopropargylphosphonates have been synthesized by using a silver(I) triflate-catalyzed one-pot three-component reaction of terminal alkynes, p-anisidine, and diethyl formylphosphonate hydrate. Good to excellent yields of the desired products may be obtained with a very simple procedure.