Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.

Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.
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DOI:
10.1126/stke.2222004pe8
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发表时间:
2004-02-24
期刊:
Science's STKE : signal transduction knowledge environment
影响因子:
--
通讯作者:
Kohn, Kurt W
Kohn, Kurt W
中科院分区:
其他
文献类型:
--
作者:
Aladjem, Mirit I;Pasa, Stefania;Kohn, Kurt W

文献摘要

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分子相互作用图(MIMs)使用一种清晰、准确和通用的图形语言来描述复杂的生物过程。在这里,我们将讨论MIM语言的主要特性及其潜在用途。MIMs可以用作数据库资源和模拟指南,并可以用于产生关于特定分子在控制细胞周期、分化和细胞死亡进程的生物调节网络中的作用的新假设。
Molecular interaction maps (MIMs) use a clear, accurate, and versatile graphical language to depict complex biological processes. Here, we discuss the main features of the MIM language and its potential uses. MIMs can be used as database resources and simulation guides, and can serve to generate new hypotheses regarding the roles of specific molecules in the bioregulatory networks that control progression through the cell cycle, differentiation, and cell death.