Comparison of the motor development of school-age children born to mothers with and without diabetes mellitus
Comparison of the motor development of school-age children born to mothers with and without diabetes mellitus
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DOI：
10.1300/j006v20n01_04
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发表时间：
2000-01-01
影响因子：
2.1
通讯作者：
Ornoy, Asher
中科院分区：
文献类型：
--
作者：
Ratzon, Navah;Greenbaum, Charles;Ornoy, Asher
本研究的目的是研究妊娠期糖尿病对后代长期运动发育的影响，并研究血糖控制与运动发育之间可能存在的相关性。我们比较了57名5- 12岁儿童的运动发育，这些儿童由48名糖尿病控制良好的母亲所生，与57名对照儿童的运动发育，这些儿童的年龄、出生顺序和父母的社会经济地位相匹配。在Bruininks-Oseretsky运动能力测试中，患有糖尿病的母亲所生的孩子在精细和大运动功能方面的表现不如对照组。母亲患有糖尿病的孩子的测试成绩与血糖水平和乙尿的严重程度呈负相关。糖尿病母亲的孩子的运动能力与生物和环境变量有很高的相关性。这些结果表明，怀孕期间的糖尿病可能会影响发育中的大脑，导致长期轻度运动缺陷。这种影响似乎是由糖尿病代谢因子的不良作用引起的，并且这种影响与糖尿病的控制程度有关。糖尿病妇女的代谢功能与家庭环境的结合可能影响其子女的运动发育。
The objectives of this study were to examine the effects of diabetes during pregnancy on the long-term motor development of the offspring and to study possible correlations between glycemic control and motor development. We compared the motor development of 57 children, 5- to 12-years-of-age, born to 48 mothers with well-controlled diabetes, to the motor development of 57 control children matched by age, birth order, and parental socio-economic status. Children born to mothers with diabetes performed less well than controls in fine and gross motor functions on the Bruininks-Oseretsky Test of Motor Proficiency. A negative correlation existed between the test scores of the children whose mothers had diabetes and the severity of hyperglycemia as assessed by blood glycosylated hemoglobin levels and acetonuria. Motor ability of the children of mothers with diabetes had a high correlation with biological and environmental variables. These results suggest that diabetes during pregnancy may affect the developing brain, inducing long-term mild motor deficiency. The effects seem to result from the adverse effects of diabetic metabolic factors, and the effects correlate with the degree of diabetes control. The combination of metabolic functioning of women with diabetes and home environment may affect the motor development of their children.