Clinicopathological Properties of the Superficial Spreading Type Early Gastric Cancer
Clinicopathological Properties of the Superficial Spreading Type Early Gastric Cancer
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DOI：
10.1007/s11605-009-1059-4
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发表时间：
2010-01-01
影响因子：
3.2
通讯作者：
Hanazaki, Kazuhiro
中科院分区：
文献类型：
--
作者：
Namikawa, Tsutomu;Kitagawa, Hiroyuki;Hanazaki, Kazuhiro
我们调查了浅表扩散型早期胃癌（EGC）与普通型EGC之间的特征差异。我们回顾性分析了1982年至2008年期间在高知医学院治疗的EGC患者的临床报告。646例患者中有61例（9.6%）为浅表扩散型EGC。弥漫型组织学类型和淋巴结转移在浅表扩散型中的发生率明显高于普通型。局限于粘膜的EGC在淋巴结阳性的浅表扩散型中的发生率明显高于淋巴结阳性的普通型，无论肿瘤浸润程度如何，浅表扩散型EGC的淋巴结转移均更明显。因此，浅表扩散型EGC的根治性切除需要适当的广泛淋巴结清扫和广泛的手术切除。
We investigated differences in characteristics between the superficial spreading type early gastric cancer (EGC) characterized by a wide and superficial extension and the common type EGC.Between 1982 and 2008, we retrospectively reviewed clinical reports of patients with the EGC treated at Kochi Medical School.Sixty-one patients (9.6%) out of 646 patients had the superficial spreading type EGC. The occurrences of diffuse type histology and lymph node metastasis were significantly greater in the superficial spreading type than in the common type. The incidence of EGC confined to the mucosa was significantly greater in the lymph node-positive superficial spreading type than in the lymph node-positive common type.In patients with the superficial spreading type EGC, lymph node metastasis was more prominent regardless of the degree of tumor invasion. Therefore, appropriate extensive lymph node dissection and wide surgical resection are required for the curative resection of the superficial spreading type EGC.