Magnetic Resonance Imaging Guidance Mitigates the Effects of Intrafraction Prostate Motion During Stereotactic Body Radiotherapy for Prostate Cancer.
Magnetic Resonance Imaging Guidance Mitigates the Effects of Intrafraction Prostate Motion During Stereotactic Body Radiotherapy for Prostate Cancer.
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DOI：
10.7759/cureus.2442
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发表时间：
2018-04-06
期刊：
影响因子：
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通讯作者：
Steinberg ML
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文献类型：
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作者：
Hegde JV;Cao M;Yu VY;Kishan AU;Shaverdian N;Lamb J;Steinberg ML
用于确定性前列腺癌治疗的立体定向体部放射治疗（SBRT）的准确递送由分次内图像引导辅助。用于分次内成像的常见方法需要侵入性地放置基准标记或电磁应答器。最近，磁共振成像（MRI）引导的三钴-60头部放射治疗系统已可用于治疗，其可以利用实时电影MRI来非侵入性地跟踪前列腺运动。我们报告了一个临床小插曲，使用这种技术提供SBRT的确定性治疗中危前列腺癌。结合MRI引导的放射治疗系统和实时自适应剂量输送的实施，考虑到分次内解剖运动，可以改善使用这种技术的结果。
The accurate delivery of stereotactic body radiotherapy (SBRT) for definitive prostate cancer treatment is aided by intrafraction image guidance. The common methods for intrafraction imaging require the invasive placement of fiducial markers or electromagnetic transponders. Recently, a magnetic resonance imaging (MRI)-guided tri-cobalt-60 head radiotherapy system has become available for treatment, which can utilize real-time cine MRI to non-invasively track prostate motion. We report on a clinical vignette using this technique to deliver SBRT for the definitive treatment of intermediate-risk prostate cancer. The incorporation of an MRI-guided radiotherapy system and the implementation of real-time adaptive dose delivery accounting for intrafraction anatomic motion may improve outcomes using this technique.