Omicron SARS-CoV-2 new variant: global prevalence and biological and clinical characteristics
Omicron SARS-CoV-2 new variant: global prevalence and biological and clinical characteristics
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DOI：
10.26355/eurrev_202112_27652
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发表时间：
2021-01-01
影响因子：
3.3
通讯作者：
Klonoff, D. C.
中科院分区：
文献类型：
--
作者：
Meo, S. A.;Meo, A. S.;Klonoff, D. C.
目的：严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)在全球范围内造成了挑战和威胁。SARS-CoV-2体现了不同的流行病学趋势，以及新出现和重新出现的病原学特征，这些特征引起了公众的极大关注。本研究旨在调查引起国际关注和恐惧的SARS-CoV-2新变种奥米克隆的全球流行、生物学和临床特征。材料和方法：从世界卫生组织(WHO)、疾病控制和预防中心(CDC)、欧洲疾病预防和控制中心(ECDC)、研究机构和全球国际印刷媒体获得关于新变种Omicron暴发的数据。我们记录了2021年11月24日至12月9日SARS-CoV-2新变种Omicron的流行情况、生物学和临床特征。结果：自2021年11月24日出现首例SARS-CoV-2变种以来，全球已有57个国家和地区发现了新的SARS-CoV-2变种，2021年12月9日报告了2152例确诊病例。全球确诊的奥米克龙变异病例数量大幅增加。这种新奇的变种正在迅速传播，并已跨越了世界各地的许多边界。新变种SARS-CoV-2的传播速度远快于其他变种SARS-CoV-2。结论：新变种SARS-CoV-2具有新的流行病学和生物学特征，比其他变种SARS-CoV-2具有更强的传染性。在短短两周的时间里，它已经影响了57个国家的2152人。然而，SARS-CoV-2 Omicron变种的病死率尚未报道。这种新变种的主要临床表现是“轻度感染”，包括头痛、身体疼痛、肌肉疼痛、咳嗽、发热、全身肌肉痛和严重疲劳。它比以前的变种感染更多的是年轻人和中年人。世界各地的卫生机构应立即采取预防措施，阻止这种新出现和重新出现的致病变种在全球范围内暴发，以最大限度地减少对人类的疾病负担。
OBJECTIVE: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has created a challenging and threatening situation worldwide. The SARS-CoV-2 embodies diverse epidemiological trends, alongside emerging and reemerging pathogenic characteristics, which have raised great public health concerns. This study aims to investigate the global prevalence, biological and clinical characteristics of Omicron, a new variant of SARS-CoV-2 that is causing concern and fear internationally.MATERIALS AND METHODS: The data on the outbreak of the new variant "Omicron" was obtained from the World Health Organization ( WHO), Centers for Disease Control and Prevention (CDC), European Centre for Disease Prevention and Control (ECDC), research institutes, and global international print media. We recorded information on the prevalence, the biological and clinical characteristics of the Omicron Variant of SARS-CoV-2 from November 24 to December 9, 2021.RESULTS: Worldwide, the new variant of SARS-CoV-2, Omicron, has been identified in 57 countries with 2152 confirmed cases reported on December 9, 2021, ever since the emergence of the first case of this variant dated November 24, 2021. The number of confirmed Omicron variant cases has significantly increased globally. The novel variant is spreading swiftly and has crossed many borders all around the world. This new variant has been observed to be transmitted far more rapidly than other variants of SARS-CoV-2.CONCLUSIONS: The new variant of SARS-CoV-2 has novel epidemiological and biological characteristics, making it more contagious than other variants of SARS-CoV-2. It has affected 2152 people in 57 countries in a short period of two weeks. However, the fatality rate of the SARS-CoV-2 Omicron variant has not yet been reported. The major clinical manifestations in this new variant are those of a "mild infection", including headache, body ache, muscles ache, cough, fever, generalized myalgia, and severe fatigue. It is infecting younger and middle-aged people more than previous variants. Worldwide health establishments should take immediate preventive measures to stop outbreaks of this emerging and reemerging pathogenic variant across the globe to minimize the disease burden on humanity.