Detecting small amounts of gene flow from phylogenies of alleles.
Detecting small amounts of gene flow from phylogenies of alleles.
复制标题
从等位基因的系统发育中检测少量基因流。
DOI：
10.1093/genetics/121.3.609
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发表时间：
1989
期刊：
影响因子：
3.3
通讯作者：
Slatkin,M
中科院分区：
文献类型：
--
作者：
Slatkin,M
合并的方法被用来找出从一个群体中抽样的等位基因的祖先都不是移民的概率。如果来自两个或更多种群的样本是这样的话，那么这些等位基因的系统发育与它们来自的地理位置之间就会有一致性。在对自然种群线粒体DNA的几项研究中，已经发现了这种类型的一致性。结果表明，如果每个种群的样本序列数量相当大(10个或更多)，那么这种类型的一致性表明种群之间迁移的平均个体数量可能相对较小(Nm<1)，但不能排除偶尔迁移的可能性。该方法被应用于E.Bermingham和J.C.Avise对弓鳍亚目Amia Calva线粒体DNA的研究。
The method of coalescents is used to find the probability that none of the ancestors of alleles sampled from a population are immigrants. If that is the case for samples from two or more populations, then there would be concordance between the phylogenies of those alleles and the geographic locations from which they are drawn. This type of concordance has been found in several studies of mitochondrial DNA from natural populations. It is shown that if the number of sequences sampled from each population is reasonably large (10 or more), then this type of concordance suggests that the average number of individuals migrating between populations is likely to be relatively small (Nm less than 1) but the possibility of occasional migrants cannot be excluded. The method is applied to the data of E. Bermingham and J. C. Avise on mtDNA from the bowfin, Amia calva.