Specific blaCTX-M-8/IncI1 Plasmid Transfer among Genetically Diverse Escherichia coli Isolates between Humans and Chickens
Specific blaCTX-M-8/IncI1 Plasmid Transfer among Genetically Diverse Escherichia coli Isolates between Humans and Chickens
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DOI：
10.1128/aac.00663-17
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发表时间：
2017-06-01
影响因子：
4.9
通讯作者：
Arakawa, Yoshichika
中科院分区：
文献类型：
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作者：
Norizuki, Chihiro;Wachino, Jun-ichi;Arakawa, Yoshichika
我们研究了从人类粪便样本和鸡肉中回收的 14 株 bla(CTX-M-8) 阳性大肠杆菌分离株的遗传主链。所有分离株均携带带有 bla(CTX-M-8) 的 IncI1 质粒 (bla(CTX-M-8)/IncI1)，大多数 (9/14) 属于特定遗传谱系，即质粒序列类型 113 (pST113)。无论来源如何，九个 bla(CTX-M-8)/IncI1 pST113 质粒的遗传背景都是相似的。这些结果表明 bla(CTX-M-8)/IncI1 可能在人类和具有遗传多样性大肠杆菌的鸡之间进行局部转移。
We investigated the genetic backbones of 14 bla(CTX-M-8)-positive Escherichia coli isolates recovered from human stool samples and chicken meat. All isolates carried IncI1 plasmids with bla(CTX-M-8) (bla(CTX-M-8)/IncI1), and most (9/14) belonged to a specific genetic lineage, namely, plasmid sequence type 113 (pST113). The genetic contexts of the nine bla(CTX-M-8)/IncI1 pST113 plasmids were similar, regardless of the source. These results suggest the probable local transfer of bla(CTX-M-8)/IncI1 between humans and chickens with genetically diverse E. coli.