HEART PERIOD VARIABILITY DURING ESTROGEN EXPOSURE AND WITHDRAWAL IN FEMALE RATS
HEART PERIOD VARIABILITY DURING ESTROGEN EXPOSURE AND WITHDRAWAL IN FEMALE RATS
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DOI：
10.1016/0031-9384(81)90184-0
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发表时间：
1981-01-01
影响因子：
2.9
通讯作者：
CARTER, CS
中科院分区：
文献类型：
--
作者：
MCCABE, PM;PORGES, SW;CARTER, CS
Heart period, heart period variability, and an estimate of vagal tone were evaluated during estrogen exposure and withdrawal in ovariectomized, freely moving female rats. Spectral analysis was used to quantify the respiratory component of heart period variability (.cxa.V), which is sensitive to alterations of vagal tone to the heart. During estrogen withdrawal, .cxa.V decreased significantly and was accompanied by a decrease in heart period. There were no significant differences in heart period or .cxa.V between the experimental (estrogen) group and the control (no estrogen) group during estrogen exposure. Total heart period variability did not differ significantly from controls during estrogen withdrawal but it did exhibit an increase during estrogen exposure. .cxa.V appeared to be more sensitive to changes in estrogen levels than total heart period variability. Decreases in cardiac vagal tone and heart rate evidently occur during estrogen withdrawal.
