Prevalence and Determinants of High-Risk Human Papillomavirus Infection in Middle-Aged Indian Women
Prevalence and Determinants of High-Risk Human Papillomavirus Infection in Middle-Aged Indian Women
复制标题
印度中年女性高危人乳头瘤病毒感染的患病率和决定因素
DOI：
10.1097/olq.0b013e318223be5f
复制
发表时间：
2011
影响因子：
3.1
通讯作者：
R. Sankaranarayanan
中科院分区：
文献类型：
--
作者：
C. Sauvaget;B. Nene;K. Jayant;R. Kelkar;Sylla G. Malvi;S. Shastri;R. Sankaranarayanan
背景：尽管宫颈癌的发病率和死亡率很高，但对西印度女性人乳头瘤病毒（HPV）感染的流行率和决定因素知之甚少。方法：收集宫颈标本，并对生活在印度马哈拉施特拉邦农村地区的 27,192 名 30 至 59 岁已婚女性进行生活方式和生殖因素调查问卷。使用第二代杂交捕获 II 检测评估高危 HPV 类型的 HPV-DNA 状态。结果：该人群中年女性HPV感染率为10.3%。高危 HPV 感染与年龄增长、教育水平低、体力劳动、第一次性交年龄过早、丧偶或分居有关。结论：社会经济地位低下和寡妇、分居妇女等社会弱势群体感染HPV的风险较高。这项研究再次证明HPV感染和随后的宫颈癌是社会疾病。
Background: Little is known about the prevalence and determinants of human papillomavirus (HPV) infection in women from West India, although incidence of and mortality from cervical cancer is high. Methods: Cervical specimens were collected, and questionnaires on lifestyle and reproductive factors were administered to 27,192 ever-married women aged 30 to 59 years living in a rural area of Maharashtra State, India. HPV-DNA status for high-risk HPV types was assessed using the second-generation hybrid-capture II assay. Results: The prevalence of HPV infection was 10.3% in this population of middle-aged women. High-risk HPV infection was associated with increasing age, low education level, manual work, early age at first sexual intercourse, and widowhood or separation. Conclusion: Low socioeconomic status and vulnerable social groups such as widows and separated women are at a higher risk of HPV infection. This study demonstrates once again that HPV infection and subsequent cervical cancer are social diseases.
DOI：
10.1097/00006254-200010000-00016
发表时间：
2000-03
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
R. Herrero;A. Hildesheim;Concepcion Bratte;M. Sherman;M. Hutchinson;J. Morales;I. Balmaceda;M. Gre
通讯作者：
R. Herrero;A. Hildesheim;Concepcion Bratte;M. Sherman;M. Hutchinson;J. Morales;I. Balmaceda;M. Gre
影响因子：
10.3
作者：
Cecilia Rodriguez, Ana;Schiffman, Mark;Burk, Robert D.
通讯作者：
Burk, Robert D.