Regulation of flowering transition by alternative splicing: the role of the U2 auxiliary factor
Regulation of flowering transition by alternative splicing: the role of the U2 auxiliary factor
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选择性剪接对开花过渡的调控：U2辅助因子的作用
DOI：
10.1093/jxb/erz416
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发表时间：
2020
影响因子：
6.9
通讯作者：
Wang Xiu-Ling
中科院分区：
文献类型：
--
作者：
Wang Yu-Yi;Xiong Feng;Ren Qiu-Ping;Wang Xiu-Ling
开花转换受复杂的遗传网络调控，响应内源和环境信号。前体mRNA剪接是基因表达转录后调控的重要步骤。在过去的十年里，人们对关键开花基因的选择性剪接进行了详细的研究。然而，很少有剪接因子被确定为参与开花转变。人异源二聚体剪接因子U2 snRNP辅助因子（U2 AF）由U2 AF 35和U2 AF 65两个亚基组成，在mRNA剪接中起3′剪接位点识别作用。最近的研究表明，拟南芥U2 AF 65 a/bandU 2AF 35 a/bandU本文主要从拟南芥U2 AF在室温下开花相关基因剪接和脱落酸信号通路中的作用两个方面综述了剪接调控开花转变的研究进展。
Flowering transition is regulated by complex genetic networks in response to endogenous and environmental signals. Pre-mRNA splicing is an essential step for the post-transcriptional regulation of gene expression. Alternative splicing of key flowering genes has been investigated in detail over the past decade. However, few splicing factors have been identified as being involved in flowering transition. Human heterodimeric splicing factor U2 snRNP auxiliary factor (U2AF) consists of two subunits, U2AF35 and U2AF65, and functions in 3′ splice site recognition in mRNA splicing. Recent studies reveal that ArabidopsisU2AF65a/bandU2AF35a/bplay important roles in the splicing of key flowering genes. We summarize recent advances in research on splicing-regulated flowering transition by focusing on the role of Arabidopsis U2AF in the splicing of key flowering-related genes at ambient temperature and in the abscisic acid signaling pathways.