Global ocean lipidomes show a universal relationship between temperature and lipid unsaturation
Global ocean lipidomes show a universal relationship between temperature and lipid unsaturation
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DOI：
10.1126/science.abn7455
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发表时间：
2022-06-24
期刊：
影响因子：
56.9
通讯作者：
Van Mooy, Benjamin A. S.
中科院分区：
文献类型：
--
作者：
Holm, Henry C.;Fredricks, Helen F.;Van Mooy, Benjamin A. S.
利用“组学”技术对浮游生物群落进行全球范围的调查，彻底改变了我们对海洋的认识。脂质组学已证明有潜力进一步深入了解海洋生态系统功能，但尚未在全球范围内应用。我们使用统一的高分辨率精确质谱分析工作流程分析了全球海洋中的930个脂质样本，揭示了海洋中脂质体的先前未知特征。集中在10种分子多样的甘油酯类，我们鉴定了1151种不同的脂质种类，发现脂肪酸不饱和度（即，碳-碳双键的数目）基本上受温度限制。我们预测，在下一个世纪，必需脂肪酸二十碳五烯酸将大幅下降，这可能对经济上至关重要的渔业产生严重的有害影响。
Global-scale surveys of plankton communities using "omics" techniques have revolutionized our understanding of the ocean. Lipidomics has demonstrated the potential to add further essential insights on ocean ecosystem function but has yet to be applied on a global scale. We analyzed 930 lipid samples across the global ocean using a uniform high-resolution accurate-mass mass spectrometry analytical workflow, revealing previously unknown characteristics of ocean planktonic lipidomes. Focusing on 10 molecularly diverse glycerolipid classes, we identified 1151 distinct lipid species, finding that fatty acid unsaturation (i.e., number of carbon-carbon double bonds) is fundamentally constrained by temperature. We predict substantial declines in the essential fatty acid eicosapentaenoic acid over the next century, which are likely to have serious deleterious effects on economically critical fisheries.