Clinical features of otolith organ-specific vestibular dysfunction
Clinical features of otolith organ-specific vestibular dysfunction
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DOI：
10.1016/j.clinph.2017.11.006
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发表时间：
2018-01-01
影响因子：
4.7
通讯作者：
Iwasaki, Shinichi
中科院分区：
文献类型：
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作者：
Fujimoto, Chisato;Suzuki, Sayaka;Iwasaki, Shinichi
目的：阐明半规管功能正常的耳石器官功能障碍患者的临床特征和前庭症状。方法：我们回顾了连续277例接受颈部和眼部前庭诱发肌源性电位测试的平衡障碍新患者的临床记录（cVEMPs和oVEMPs）以及热量测试和视频头部脉冲测试（vHIT）。我们确定了76名患者，他们在每个SCC平面中显示正常的热量反应和正常的vHIT结果，但在cVEMP和/或oVEMP测试中显示异常反应。良性阵发性位置性眩晕（BPPV）是最常见的诊断。37%的患者不能被归类为任何可能导致平衡障碍的临床实体，并且没有表现出感音神经性听力损失。特发性病例最常见的临床表现是反复发作的旋转性眩晕，持续时间为1-12 h。结论：耳石器官特异性前庭功能障碍最常见的诊断是BPPV。特发性眩晕最常见的临床表现为反复发作的旋转性眩晕。(C)2017年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: To elucidate the clinical features and vestibular symptoms of patients with otolith organ dysfunction in the presence of normal function of the semicircular canals.Methods: We reviewed the clinical records of 277 consecutive new patients with balance disorders who underwent testing of cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs) as well as caloric testing and video head impulse testing (vHIT).Results: We identified 76 patients who showed normal caloric responses and normal vHIT findings in each SCC plane, but abnormal responses in cVEMP and/or oVEMP testing. Benign paroxysmal positional vertigo (BPPV) was the most common diagnosis. 37% of patients could not be categorized into any of the established clinical entities that could cause a balance disorder and did not show sensorineural hearing loss. The most common clinical manifestation in the idiopathic cases was recurrent rotatory vertigo with a duration of 1-12 h.Conclusions: The most common diagnosis of otolith organ-specific vestibular dysfunction was BPPV. The most common clinical manifestation in the idiopathic cases was recurrent rotatory vertigo. (C) 2017 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.