CENTRAL AUDITORY FUNCTION IN ALZHEIMERS-DISEASE
CENTRAL AUDITORY FUNCTION IN ALZHEIMERS-DISEASE
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DOI：
10.1212/wnl.35.3.352
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发表时间：
1985-01-01
期刊：
影响因子：
9.9
通讯作者：
PATRONAS, NJ
中科院分区：
文献类型：
--
作者：
GRIMES, AM;GRADY, CL;PATRONAS, NJ
38例老年性痴呆患者的中枢听觉（两耳分听）功能与对照组相比明显受损。两耳分听评分与智商、颞叶皮质萎缩及左颞叶脑葡萄糖代谢相关。比较颞叶的萎缩和葡萄糖代谢，观察到对侧耳的影响，在两分的性能，以及相互作用的不对称性的萎缩与两分的性能，与以前的模型的两分听其他形式的颞叶病理。
The central auditory (dichotic) function of 38 patients with Alzheimer''s disease was significantly impaired when compared with a control group. Significant relationships were observed between dichotic scores and intelligence quotient, cortical atrophy in the temporal lobes and cerebral glucose metabolism in the left temporal lobe. Comparing atrophy and glucose metabolism in the temporal lobes, contralateral ear effects were observed in dichotic performance as well as an interaction of asymmetry of atrophy with dichotic performance, consistent with previous models of dichotic listening in other forms of temporal lobe pathology.