Association of potato consumption with calcified atherosclerotic plaques in the coronary arteries: The NHLBI Family Heart Study.
Association of potato consumption with calcified atherosclerotic plaques in the coronary arteries: The NHLBI Family Heart Study.
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食用马铃薯与冠状动脉钙化动脉粥样硬化斑块的关联：NHLBI 家庭心脏研究。
DOI：
10.1016/j.numecd.2023.07.027
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Djousse,Luc
中科院分区：
文献类型：
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作者：
Qavi,AhmedHassaan;Zhou,Guohai;Ward,RachelE;Carr,JohnJeffrey;Ellison,RCurtis;Arnett,DonnaK;Gaziano,JMichael;Djousse,Luc
背景和目的虽然土豆摄入量与冠状动脉疾病危险因素之间的联系并不一致，但关于土豆摄入量对亚临床疾病的影响的文献中还没有数据。因此，我们试图检查食用烤土豆/土豆泥是否与冠状动脉中钙化的动脉粥样硬化斑块有关。方法和结果：在横断面设计中，我们研究了NHLBI家族心脏研究的2208名参与者。这些受试者是根据他们与普通人群相比心血管疾病风险较高的情况而选择的。土豆消费量通过半定量食物频率问卷进行评估。我们使用至少100分的Agatston评分来定义流行的CAC，并拟合通用估计方程来计算CAC的流行优势比。初次就诊的平均年龄为58.2岁，其中55%为女性。土豆消费量的中位数是每周2-4个。食用土豆的频率与CAC的流行之间没有统计学意义的相关性：在报告土豆消费量的受试者中，CAC的优势比(95%CI)分别为1.0(参考)、0.85(0.56-1.30)、0.85(0.58-1.26)和0.95(0.60-1.53)；分别为每周1次、每周1次、每周2次和每周5次(p为线性趋势0.83)，调整了年龄、性别、BMI、吸烟、锻炼、糖尿病、高血压、总卡路里、冠心病患病率、收入、教育程度和每日红肉摄入量。结论我们在老年人中未发现烤土豆/土豆泥的摄入量与CAC显著相关。研究报名日期：5/25/2000。
Background and aimsWhile the association of potato consumption with risk factors for coronary artery disease has been inconsistent, no data are available in the literature on the influence of potato consumption on subclinical disease. Thus, we sought to examine whether baked/mashed potato consumption is associated with calcified atherosclerotic plaques in the coronary arteries.Methods and ResultsIn a cross-sectional design, we studied 2208 participants of the NHLBI Family Heart Study. These subjects were selected based on their elevated cardiovascular disease risk compared to the general population. Potato consumption was assessed by a semi-quantitative food frequency questionnaire. We defined prevalent CAC using an Agatston score of at least 100 and fitted generalized estimating equations to calculate prevalence odds ratios of CAC. Mean age at initial clinic visit was 58.2 years and 55% were female. Median consumption of potatoes was 2–4/week. There was no statistically significant association between frequency of potato consumption and prevalent CAC: odds ratios (95% CI) for CAC were 1.0 (reference), 0.85 (0.56–1.30), 0.85 (0.58–1.26), and 0.95 (0.60–1.53) among subjects reporting potato consumption of <1/week, 1/week, 2–4/week, and 5+/week, respectively (p for linear trend 0.83), adjusting for age, sex, BMI, smoking, exercise, diabetes, hypertension, total calories, prevalent coronary heart disease, income, education, and daily red meat intake.ConclusionsWe found no significant association between baked/mashed potato consumption and CAC in older adults.Study registration numberNCT00005136. Study registration date: 5/25/2000.