REFLEX BLADDER ACTIVITY INDUCED BY ELECTRICAL-STIMULATION OF HINDLIMB SOMATIC AFFERENTS IN THE CAT
REFLEX BLADDER ACTIVITY INDUCED BY ELECTRICAL-STIMULATION OF HINDLIMB SOMATIC AFFERENTS IN THE CAT
复制标题
DOI：
10.1016/0165-1838(80)90019-3
复制
发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
SCHMIDT, RF
中科院分区：
文献类型：
--
作者：
SATO, A;SATO, Y;SCHMIDT, RF
在膀胱反射反应的研究中使用的方法和获得的结果如下。在氯醛糖-乌拉坦麻醉猫上，用气囊法连续记录膀胱内压。电刺激后肢皮肤和肌肉神经的各种传入纤维，并检查由此产生的膀胱功能变化。当膀胱几乎是空的和静止的，重复刺激组III（薄髓鞘）和IV（无髓鞘）的皮肤或肌肉传入纤维的后肢神经引起反射增加膀胱紧张。这种躯体-膀胱兴奋性反射是固有脊髓性的，其传出弧主要在盆神经，当扩张的膀胱有自发的、大的（振幅在300-400 mm H2O以上）、节律性的（约1.0-2.5次/min）排尿收缩时，这些收缩被重复刺激后肢神经的III和IV组皮肤或肌肉传入纤维所抑制。抑制有时随后较大的排尿收缩。这种躯体-膀胱抑制反射的传出弧也在盆神经中。脊髓上的结构是必不可少的排尿收缩;刺激组III和IV传入纤维一起比刺激组III传入纤维单独激活兴奋性或抑制性体膀胱反射通路更有效。
Methods used and results obtained in a study fo reflex responses of the bladder were as follows. Intravesical pressure was reocrded continuously by the balloon method in chloralose-urethane anesthetized cats. Various afferent fibers of hind limb cutaneous and muscle nerves were stimulated electrically, and the resulting changes in vesical functions were examined. When the bladder was nearly empty and quiescent, repetitive stimulation of group III (thin myelinated) and IV (non-myelinated) cutaneous or muscle afferent fibers of hind limb nerves caused a reflex increase in the vesical tonus. This somato-vesical excitatory reflex was propriospinal with its efferent arc mainly in the pelvic nerves; when there were spontaneous, large (amplitude above 300-400 mm H2O), rhythmic (about 1.0-2.5/min) micturition contractions of the expanded bladder, these contractions were inhibited by repetitive stimulation of the group III and IV cutaneous or muscle afferent fibers of hind limb nerves. The inhibition was sometimes followed by subsequent larger micturition contractions. The efferent arc for this somato-vesical inhibitory reflex was also in the pelvic nerves. Supraspinal structures were essential for producing the micturition contractions; stimulation of group III and IV afferent fibers together was more effective than stimulation of the group III afferent fibers alone in activating either the excitatory or inhibitory somato-vesical reflex pathways.