Home compared with clinic-based screening for sexually transmitted infections: a randomized controlled trial.
Home compared with clinic-based screening for sexually transmitted infections: a randomized controlled trial.
复制标题
DOI：
10.1097/aog.0b013e3181fae60d
复制
发表时间：
2010-12
影响因子：
7.2
通讯作者：
Peipert JF
中科院分区：
文献类型：
--
作者：
Graseck AS;Secura GM;Allsworth JE;Madden T;Peipert JF
确定在使用长效可逆避孕措施的参与者中，与基于诊所的筛查相比，基于家庭的性传播感染（STI）筛查是否会导致更高的STI筛查率。我们在避孕选择项目中对使用长效可逆避孕方法的妇女进行了一项随机临床试验（n = 558）。参与者被随机分配到家庭检测（拭子邮寄到参与者的家中或诊所检测）。采用链置换分析法对自行采集的阴道拭子进行沙眼衣原体和淋病奈瑟菌检测。我们使用Poisson回归和稳健的误差方差估计了各组筛查的相对风险。除婚姻状况外，随机分组在基线时相似;诊所组的未婚女性较多（62.0%比51.6%），家庭组的离婚女性较多（12.1%比5.6%，p = 0.007）。在多变量分析中，与诊所组的女性相比，家庭组的女性更有可能自我报告筛查（56.3% vs. 32.9%，RR 1.7，95% CI 1.4 - 2.0）。当通过收到的或病历中记录的检查进行分析时，获得了相似的结果（56.3% vs. 25.0%，RR 2.2，95% CI 1.7 - 2.7）。与未完成筛查的女性相比，完成筛查的女性受教育程度更高，更有可能获得公共援助。在家中随机接受STI筛查的长效可逆避孕药使用者比随机接受传统诊所筛查的人更有可能完成筛查。以家庭为基础的筛查可能是有用的妇女使用LARC方法谁可能不存在定期筛查。
To determine whether home-based screening for sexually transmitted infections (STIs) results in a higher STI screening rate compared to clinic-based screening in participants using long-acting reversible contraception. We performed a randomized clinical trial of women using long-acting reversible contraception methods in the Contraceptive CHOICE Project (n = 558). Participants were randomly assigned to home-based testing (swabs mailed to the participant's home or clinic-based testing. Self-collected vaginal swabs were tested for Chlamydia trachomatis and Neisseria gonorrhoeae using strand displacement analysis. We estimated the relative risk of screening by group using Poisson regression with robust error variance. The randomization groups were similar at baseline, except for marital status; the clinic group had more never-married women (62.0% vs. 51.6%), and the home group had more divorced women (12.1% vs. 5.6%, p = 0.007). Women in the home group were more likely to self-report screening compared to women in the clinic group in the multivariable analysis (56.3% vs. 32.9%, RR 1.7, 95% CI 1.4 – 2.0). When analyzed by tests received or documented in medical records, similar results were obtained (56.3% vs. 25.0%, RR 2.2, 95% CI 1.7 – 2.7). Women who completed screening had higher levels of education and were more likely to receive public assistance compared to those who did not complete screening. Long-acting reversible contraception users randomized to STI screening at home were more likely to complete screening than those randomized to traditional clinic-based screening. Home-based screening may be useful in women using LARC methods who may not present for regular screening.