Anterior migration of intravitreal fluocinolone acetonide (Iluvien®) implant in a pseudophakic eye with intact posterior capsule.
Anterior migration of intravitreal fluocinolone acetonide (Iluvien®) implant in a pseudophakic eye with intact posterior capsule.
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DOI：
10.1016/j.ajoc.2020.100922
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发表时间：
2020-12
影响因子：
--
通讯作者：
Elbarky A
中科院分区：
文献类型：
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作者：
Alzaabi M;Taguri AH;Elbarky A
描述玻璃体内氟轻松（Iluvien®）植入物在后囊完整的人工晶状体眼中自发前移的病例。一名患有增殖性糖尿病视网膜病变的 60 岁女性接受了平坦部玻璃体切除术和双眼晶状体后房型人工晶状体 (PCIOL) 植入物超声乳化术。她的右眼出现糖尿病性黄斑水肿 (DME)，反复玻璃体内注射阿柏西普 2mg/0.05ml (Eylea®) 没有反应。该患者在对地塞米松玻璃体内植入物 (Ozurdex™) 表现出良好的暂时反应后，接受了玻璃体内 Iluvien® 植入物来治疗顽固性 DME。六个月后，她因眼内压 (IOP) 升高而出现右眼疼痛。研究发现，在存在完整的后囊和稳定的 PCIOL 植入物的情况下，Iluvien® 植入物被移入前房 (AC)。迁移的 Iluvien 植入物被移除，并用青光眼引流阀控制眼压，因为它无法对最大程度的抗青光眼药物产生反应。在存在完整后囊的情况下，玻璃体内 Iluvien® 植入物可以迁移到先前接受玻璃体切除术的眼睛的 AC 中。
To describe a case of spontaneous anterior migration of intravitreal fluocinolone acetonide (Iluvien®) implant in a pseudophakic eye with intact posterior capsule. A 60-year old woman with proliferative diabetic retinopathy underwent uneventful pars plana vitrectomy and phacoemulsification with posterior chamber intraocular lens (PCIOL) implants in both eyes. She developed diabetic macular edema (DME) in her right eye which failed to respond to repeated intravitreal injections of Aflibercept 2mg/0.05ml (Eylea®). The patient received an intravitreal Iluvien® implant to treat the recalcitrant DME after she showed a favorable temporary response to dexamethasone intravitreal implant (Ozurdex™).Six months later she presented with pain in the right eye due to elevated intraocular pressure (IOP). The Iluvien® implant was found to be dislodged into the anterior chamber (AC) in the presence of an intact posterior capsule and stable PCIOL implant. The migrated Iluvien implant was removed and IOP was controlled with a glaucoma drainage valve as it failed to respond to maximum anti-glaucoma medication. Intravitreal Iluvien® implant could migrate into the AC in a previously vitrectomized eyes in the presence of an intact posterior capsule.