INFLUENCE OF TEMPERATURE ON SOLUBILITY OF MONOSODIUM URATE

INFLUENCE OF TEMPERATURE ON SOLUBILITY OF MONOSODIUM URATE
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DOI:
10.1002/art.1780150209
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发表时间:
1972-01-01
影响因子:
--
通讯作者:
LOEB, JN
LOEB, JN
中科院分区:
其他
文献类型:
--
作者:
LOEB, JN

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在存在生理钠浓度的情况下,尿酸钠的有限溶解度随着温度的降低而急剧下降。提示这一现象可能与临床上观察到的痛风石分布和某些关节对急性痛风性关节炎的易感性有关。
The limited solubility of monosodium urate in the presence of physiological sodium concentrations is shown to fall sharply with decreasing temperature. It is suggested that this phenomenon may play a role in determining the clinically observed distribution of tophi and the susceptibility of certain joints to acute gouty arthritis.