Interactive Bio-feedback Therapy Using Hybrid Assistive Limbs for Motor Recovery after Stroke: Current Practice and Future Perspectives.
Interactive Bio-feedback Therapy Using Hybrid Assistive Limbs for Motor Recovery after Stroke: Current Practice and Future Perspectives.
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DOI：
10.2176/nmc.st.2016-0094
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发表时间：
2016-10-15
影响因子：
1.9
通讯作者：
Inoue T
中科院分区：
文献类型：
--
作者：
Morishita T;Inoue T
交互式生物反馈（iBF）最初是为神经系统疾病患者的运动功能康复而开发的，随后产生了混合辅助肢体（HAL）的开发。在这里，我们对HAL治疗的基础理论以及我们的临床经验进行了回顾，并对未来使用HAL治疗急性中风患者的临床研究提出了建议。我们进行了基于PubMed的文献检索，对我们的急性卒中病例系列进行了回顾性数据审查，并纳入了我们发现的样本病例报告。鉴于过去的动物研究和功能成像结果，在中风急性期使用HAL的iBF治疗似乎是预防学习性不使用和半球间兴奋失衡的适当方法。iBF疗法还可促进适当的神经元网络重组。根据我们中风中心的经验，HAL康复是一种安全有效的治疗方式，用于恢复急性中风后的运动障碍，并允许为个体患者设计量身定制的康复计划。通过HAL系统的iBF治疗似乎是一种有效且有前途的卒中康复方法;然而，这种治疗相对于传统康复的优越性仍不清楚。进一步的临床研究是必要的。此外，患者登记的形成将允许对HAL病例进行荟萃分析，并解决与对照试验相关的问题（例如，急性卒中队列的异质性）。机器人工程的发展将提高HAL康复的疗效，并有可能使患者康复实践标准化。
Interactive bio-feedback (iBF) was initially developed for the rehabilitation of motor function in patients with neurological disorders, and subsequently yielded the development of the hybrid assistive limb (HAL). Here, we provide a review of the theory underlying HAL treatment as well as our clinical experience and recommendations for future clinical studies using HAL in acute stroke patients. We performed a PubMed-based literature search, a retrospective data review of our acute stroke case series, and included a sample case report of our findings. Given past animal studies and functional imaging results, iBF therapy using the HAL in the acute phase of stroke seems an appropriate approach for preventing learned non-use and interhemispheric excitation imbalances. iBF therapy may furthermore promote appropriate neuronal network reorganization. Based on experiences in our stroke center, HAL rehabilitation is a safe and effective treatment modality for recovering motor impairments after acute stroke, and allows the design of tailored rehabilitation programs for individual patients. iBF therapy through the HAL system seems to be an effective and promising approach to stroke rehabilitation; however, the superiority of this treatment to conventional rehabilitation remains unclear. Further clinical studies are warranted. Additionally, the formation of a patient registry will permit a meta-analysis of HAL cases and address the problems associated with a controlled trial (e.g., the heterogeneity of an acute stroke cohort). The development of robotic engineering will improve the efficacy of HAL rehabilitation and has the potential to standardize patient rehabilitation practice.
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影响因子：
1.9
作者：
Ogata T;Abe H;Samura K;Hamada O;Nonaka M;Iwaasa M;Higashi T;Fukuda H;Shiota E;Tsuboi Y;Inoue T
通讯作者：
Inoue T
影响因子：
2.9
作者：
Morishita T;Inoue T
通讯作者：
Inoue T
中风后与新外骨骼 - 混合辅助肢体：安全性和可行性的研究。
影响因子：
5.1
作者：
Nilsson A;Vreede KS;Häglund V;Kawamoto H;Sankai Y;Borg J
通讯作者：
Borg J
影响因子：
8.3
作者：
Jauch, Edward C.;Saver, Jeffrey L.;Yonas, Howard
通讯作者：
Yonas, Howard
影响因子：
1.9
作者：
Fukuda, Hiroyuki;Samura, Kazuhiro;Inoue, Tooru
通讯作者：
Inoue, Tooru