Revised system to evaluate measurement of blood chemistry data from the Japanese National Health and Nutrition Survey and Prefectural Health and Nutrition Surveys.
Revised system to evaluate measurement of blood chemistry data from the Japanese National Health and Nutrition Survey and Prefectural Health and Nutrition Surveys.
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DOI：
10.2188/jea.je20120032
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发表时间：
2013
影响因子：
4.7
通讯作者：
Yoshiike N
中科院分区：
文献类型：
--
作者：
Nakamura M;Kiyama M;Kitamura A;Ishikawa Y;Sato S;Noda H;Yoshiike N
我们开发了一个监测系统，使用总误差 (TE) 来评估来自国家健康和营养调查 (NHNS) 和县健康和营养调查 (PHNS) 的血液化学数据的测量。 NHNS 和 PHNS 的血液化学数据由日本东京的商业实验室 SRL, Inc. 进行分析。利用外部和内部质量控制的准确性和精密度，计算了 1999 年至 2010 年期间 14 个血液化学项目的 TE。可接受范围定义为小于中位数的 80% 置信上限，不可接受范围定义为可接受范围截止值的两倍以上，边界范围定义为可接受范围和不可接受范围之间的间隔。可接受和临界范围的 TE 上限为总胆固醇 (mg/dL) 5.7%、高密度脂蛋白胆固醇 (mg/dL) 9.9%、低密度脂蛋白胆固醇 (mg/dL) 10.0%、甘油三酯 (mg/dL) 10.4%、总蛋白 (g/dL) 6.6%、白蛋白 7.6% (g/dL)、肌酐 (mg/dL) 10.8%、葡萄糖 (mg/dL) 6.5%、γ-谷氨酰转肽酶 (U/L) 9.7%、尿酸 (mg/dL) 7.7%、尿素氮 (mg/dL) 8.7%、天冬氨酸转氨酶 (U/L) 9.2%、丙氨酸转氨酶 (U/L) 为 9.5%，糖化血红蛋白 (%) 为 6.5%。该监测系统的建立是为了帮助卫生专业人员评估调查年份和地区之间NHNS和PHNS血液化学数据的连续性和可比性，并防止得出有偏见或不正确的结论。
We developed a monitoring system that uses total errors (TEs) to evaluate measurement of blood chemistry data from the National Health and Nutrition Survey (NHNS) and Prefectural Health and Nutrition Surveys (PHNS). Blood chemistry data from the NHNS and PHNS were analyzed by SRL, Inc., a commercial laboratory in Tokyo, Japan. Using accuracy and precision from external and internal quality controls, TEs were calculated for 14 blood chemistry items during the period 1999–2010. The acceptable range was defined as less than the upper 80% confidence limit for the median, the unacceptable range as more than twice the cut-off value of the acceptable range, and the borderline range as the interval between the acceptable and unacceptable ranges. The TE upper limit for the acceptable and borderline ranges was 5.7% for total cholesterol (mg/dL), 9.9% for high-density lipoprotein cholesterol (mg/dL), 10.0% for low-density lipoprotein cholesterol (mg/dL), 10.4% for triglycerides (mg/dL), 6.6% for total protein (g/dL), 7.6% for albumin (g/dL), 10.8% for creatinine (mg/dL), 6.5% for glucose (mg/dL), 9.7% for γ-glutamyl transpeptidase (U/L), 7.7% for uric acid (mg/dL), 8.7% for urea nitrogen (mg/dL), 9.2% for aspartate aminotransferase (U/L), 9.5% for alanine aminotransferase (U/L), and 6.5% for hemoglobin A1c (%). This monitoring system was established to assist health professionals in evaluating the continuity and comparability of NHNS and PHNS blood chemistry data among survey years and areas and to prevent biased or incorrect conclusions.