Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides.
Three-component coupling using arynes and DMF: straightforward access to coumarins via ortho-quinone methides.
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DOI：
10.1039/c1cc11955a
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发表时间：
2011-07
影响因子：
4.9
通讯作者：
H. Yoshida;Y. Ito;J. Ohshita
中科院分区：
文献类型：
--
作者：
H. Yoshida;Y. Ito;J. Ohshita
芳烃与DMF之间的[2+2]环加成反应生成邻苯二酮甲基化物，它很容易与酯烯醇酸盐或酮亚胺阴离子进行[4+2]环加成反应，以一种直接的方式合成各种香豆素。
ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner.