Mathematical modelling of mechano-electric feedback in cardiomyocytes
Mathematical modelling of mechano-electric feedback in cardiomyocytes
复制标题
心肌细胞机电反馈的数学模型
DOI:
10.1515/1569398041974941
复制
发表时间:
2004
影响因子:
7.8
通讯作者:
V. Markhasin
中科院分区:
文献类型:
--
作者:
O. Solovyova;N. Vikulova;P. Konovalov;P. Kohl;V. Markhasin
We earlier developed the mathematical model of electrical and mechanical activity in myocardium, which takes into account both direct coupling and feedback between excitation and contraction. In this paper, in the framework of the model we found conditions under which both the abrupt shortening and stretch of cardiac preparation can cause extra action potentials and hence anomalous deformations can be arrhythmia sources. In the framework of the model, we establish possible mechanisms underlying the Anrep phenomenon that reflects a relationship between myocardium contraction and vascular resistance in the intact heart.
影响因子:
2
作者:
Rice,JJ;Winslow,RL;Dekanski,J;McVeigh,E
通讯作者:
McVeigh,E
DOI:
--
发表时间:
2001
期刊:
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
影响因子:
--
作者:
Gordon,AM;Regnier,M;Homsher,E
通讯作者:
Homsher,E