Surprising versatility of Na+-glucose cotransporters: SLC5.
Surprising versatility of Na+-glucose cotransporters: SLC5.
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DOI：
10.1152/physiol.00026.2004
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发表时间：
2004-12
期刊：
影响因子：
8.4
通讯作者：
E. M. Wright;D. Loo;B. Hirayama;E. Turk
中科院分区：
文献类型：
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作者：
E. M. Wright;D. Loo;B. Hirayama;E. Turk
SLC5是一个古老的基因家族，在人类基因组中有11个成员。这些膜蛋白具有多种多样的功能，从主动运输溶质、离子和水，到引导水和尿素，再到在胆碱能神经元中感知葡萄糖。代谢紊乱已被确定与两个人类基因的先天性突变有关。
SLC5 is an ancient gene family with 11 members in the human genome. These membrane proteins have diverse, multiple functions ranging from actively transporting solutes, ions, and water, to channeling water and urea, to sensing glucose in cholinergic neurons. Metabolic disorders have been identified that are associated with congenital mutations in two of the human genes.