Functional connectivity in the prefrontal cortex measured by near-infrared spectroscopy during ultrarapid object recognition
Functional connectivity in the prefrontal cortex measured by near-infrared spectroscopy during ultrarapid object recognition
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DOI：
10.1117/1.3533266
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发表时间：
2011-01-01
影响因子：
3.5
通讯作者：
VanMeter, John
中科院分区：
文献类型：
--
作者：
Medvedev, Andrei V.;Kainerstorfer, Jana M.;VanMeter, John
近红外光谱（NIRS）是一种低成本、无创的脑功能成像技术。利用多通道光学仪器，不仅可以测量血红蛋白浓度的局部变化，而且可以测量不同脑区中这些变化的时间相关性，这给出了传统上由fMRI测量的功能连接的光学模拟。我们记录了血流动力学活动在Go-NoGo任务，从11个右撇子的主题与探头放置在双侧前额区。受试者在自然场景中按下鼠标按钮检测动物作为目标。对数据进行低通滤波
Near-infrared spectroscopy (NIRS) is a developing technology for low-cost noninvasive functional brain imaging. With multichannel optical instruments, it becomes possible to measure not only local changes in hemoglobin concentrations but also temporal correlations of those changes in different brain regions which gives an optical analog of functional connectivity traditionally measured by fMRI. We recorded hemodynamic activity during the Go-NoGo task from 11 right-handed subjects with probes placed bilaterally over prefrontal areas. Subjects were detecting animals as targets in natural scenes pressing a mouse button. Data were low-pass filtered