Structural features of human leukocyte interferon A as determined by circular dichroism spectroscopy.
Structural features of human leukocyte interferon A as determined by circular dichroism spectroscopy.
复制标题
圆二色光谱测定人白细胞干扰素 A 的结构特征。
DOI:
10.1111/j.1399-3011.1982.tb02658.x
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发表时间:
1982
期刊:
影响因子:
--
通讯作者:
Wetzel,R
中科院分区:
文献类型:
--
作者:
Bewley,TA;Levine,HL;Wetzel,R
The solution structure of human leukocyte (alpha) interferon‐A (LeIF‐A) purified fromE. coliextracts was investigated by circular dichroism spectroscopy. At pH 8.2, the native molecule exhibits 40–70%α‐helix and no clearly detectable β‐structure. The tertiary structure includes a closely‐packed interior containing at least one tryptophan side‐chain. Titration to pH 1.5 produces a partial loss of structural features which are rapidly regained on return to neutral pH.
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影响因子:
4.8
作者:
Theophil Staehelin;Donna S. Hobbsg;Hsiang;Chun;Sidney Pestkag
通讯作者:
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影响因子:
3.5
作者:
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DOI:
10.1016/0006-291x(80)90868-2
发表时间:
1980
影响因子:
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作者:
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通讯作者:
Hayes,TG
DOI:
--
发表时间:
1960
期刊:
影响因子:
--
作者:
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通讯作者:
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影响因子:
56.9
作者:
STREULI, M;NAGATA, S;WEISSMANN, C
通讯作者:
WEISSMANN, C