Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki–Miyaura Cross-Coupling by One-Pot Synthesis
Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki–Miyaura Cross-Coupling by One-Pot Synthesis
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使用钯碳催化的 Suzuki-Miyaura 交叉偶联一锅合成法进行芳香族化合物的二聚
DOI：
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发表时间：
2018
期刊：
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通讯作者：
Guoliang Chen
中科院分区：
文献类型：
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作者：
Fangyu Du;Qifan Zhou;Dongdong Liu;Ting Fang;Yajie Shi;Yang Du;Guoliang Chen
摘要芳香族二聚体在许多方面起着重要的作用。在此，我们报告了一个简单的钯-碳催化剂，是非常有效的溴化芳香族化合物在温和的条件下，使用丰富的溴化芳香族化合物，双（频哪醇）二硼和乙酸钾通过“一锅法”的二聚反应。我们认为该方法通过Suzuki-Miyaura交叉偶联反应机制进行，允许在温和的反应条件下获得各种芳香族化合物，并且具有良好的官能团耐受性，产率中等至高。
Abstract The aromatic dimers play a significant role in many aspects. Herein, we report a simple palladium-carbon catalyst that is highly effective for the dimerization of brominated aromatic compounds under mild conditions using abundant brominated aromatic compounds, bis(pinacolate)diboron and potassium acetate by a ‘one-pot’ method. This process, which we believe proceeds via a Suzuki–Miyaura cross-coupling reaction mechanism, allows access to a variety of aromatic compounds under mild reaction conditions and has a good functional group tolerance with moderate to high yields.