The effect of drug consultation center guidance on contraceptive use among women using isotretinoin: A randomized, controlled study
The effect of drug consultation center guidance on contraceptive use among women using isotretinoin: A randomized, controlled study
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DOI：
10.1089/jwh.2007.0623
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发表时间：
2008-05-01
影响因子：
3.5
通讯作者：
Berkovitch, Matitiahu
中科院分区：
文献类型：
--
作者：
Tsur, Lilach;Kozer, Eran;Berkovitch, Matitiahu
背景：用异托摩蛋白治疗的生殖年龄的妇女必须使用两种避孕药具，但遵守建议是有限的。我们的目标是确定药物咨询中心（DCC）的主动干预是否会增加服用异托诺蛋白的妇女的避孕药。进行干预组（在初次面试期间通过电话信息，通过邮寄的书面表格以及发送给其蜂窝电话的短信）和一个对照组（一次提供的信息）。第一次面试后3个月对所有妇女进行了后续电话。分子：一百八名妇女（干预组50名和58个对照）被招募。大多数妇女不遵守建议的避孕药使用。 3个月后，研究组的50％和40％的对照组使用避孕药（P = 0.41），每组中只有2名妇女使用了两种避孕方法：结论：提高遵守避孕药避孕的策略需要接受异毒素治疗的妇女。
Background: Women of reproductive age treated with isotretinoin are required to use two forms of contraceptives, yet adherence to the recommendations is limited. Our objective was to determine if an active intervention by a drug consultation center (DCC) will increase contraceptive use among women taking isotretinoin.Methods: In a randomized, controlled study, women of reproductive age who called the DCC seeking advice regarding isotretinoin were randomly assigned to an intervention group (information by phone during initial interview, by mailed written form, and by text messages sent to their cellular phones) and a control group (information given once). A follow-up call was made to all women 3 months after the first interview.Results: One hundred eight women (50 in the intervention group and 58 control) were enrolled. Most women do not adhere to the recommended contraceptive use. After 3 months, 50% of the study group and 40% of the control group were using a contraceptive (p = 0.41), and only 2 women in each group used two methods of contraception.Conclusions: Strategies to increase adherence to contraceptive use among women treated with isotretinoin are needed.