EXTENDED RESECTION IN THE TREATMENT OF COLORECTAL-CANCER

EXTENDED RESECTION IN THE TREATMENT OF COLORECTAL-CANCER
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DOI:
10.1007/bf00341238
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发表时间:
1991-01-01
影响因子:
2.8
通讯作者:
JAUS, M
JAUS, M
中科院分区:
医学3区
文献类型:
--
作者:
MONTESANI, C;RIBOTTA, G;JAUS, M

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1975年至1990年间,525名患者在我们的科室接受了结直肠癌切除术。其中,38例肿瘤侵入邻近结构,并接受了扩大切除。总的来说,有67例姑息治疗。其中,38名患者中有3人接受了延长切除术。当比较未根治延伸组(n = 423)和根治延伸组(n = 35)时,各自的死亡率(1.9%对0)和发病率(12.8%对11.3%)没有差异。延长切除后各自的局部复发率(13% vs 26%)显著增加。延长切除后的5年生存率为30%,与标准切除T2-3淋巴结阳性肿瘤的一般生存率没有区别。因此,对于局部晚期肿瘤,扩大切除是一种安全而重要的方法。
Between 1975 and 1990, 525 patients underwent resection of colorectal cancer in our unit. Of these, 38 had tumour invading adjacent structures and underwent an extended resection. Overall, there were 67 cases treated palliatively. Of these, three were in the group of 38 having an extended resection. When the groups of radical not extended (n = 423) and radical extended resections (n = 35) were compared, respective values for mortality (1.9% vs 0) and morbidity (12.8% vs 11.3%) were not different. Respective local recurrence rates (13% vs 26%) were significantly greater after extended resection. Five-year survival after extended resection was 30%, no different from the general survival rate for standard resections for T2-3 node-positive tumours. Extended resection is thus a safe and important approach for locally advanced tumours.