SCHIP: statistics for chromosome interphase positioning based on interchange data.
SCHIP: statistics for chromosome interphase positioning based on interchange data.
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SCHIP:基于交换数据的染色体间期定位统计。
DOI:
10.1093/bioinformatics/bti470
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发表时间:
2005
期刊:
影响因子:
--
通讯作者:
Arsuaga,Javier
中科院分区:
文献类型:
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作者:
Vives,Sergi;Loucas,Bradford;Vazquez,Mariel;Brenner,DavidJ;Sachs,RainerK;Hlatky,Lynn;Cornforth,Michael;Arsuaga,Javier
Motivation:The position of chromosomes in the interphase nucleus is believed to be associated with a number of biological processes. Here, we present a web-based application that helps analyze the relative position of chromosomes during interphase in human cells, based on observed radiogenic chromosome aberrations. The inputs of the program are a table of yields of pairwise chromosome interchanges and a proposed chromosome geometric cluster. Each can either be uploaded or selected from provided datasets. The main outputs areP-values for the proposed chromosome clusters. SCHIP is designed to be used by a number of scientific communities interested in nuclear architecture, including cancer and cell biologists, radiation biologists and mathematical/computational biologists.Availability:http://cramer.stat.ub.es/schipContact:jarsuaga@cc.ucsf.eduSupplementary information:http://cramer.stat.ub.es/schip/help.htm