Depression and anxiety in patients with hepatitis C: prevalence, detection rates and risk factors
Depression and anxiety in patients with hepatitis C: prevalence, detection rates and risk factors
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DOI：
10.1016/j.genhosppsych.2005.06.006
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发表时间：
2005-11-01
影响因子：
7
通讯作者：
Conroy, RM
中科院分区：
文献类型：
--
作者：
Golden, J;O'Dwyer, AM;Conroy, RM
目的：我们研究了一组等待干扰素治疗丙型肝炎的患者，以估计患病率和检出率和危险因素为mood disorders.Methods：DSM-IV Axis I Disorders的结构化临床访谈：临床医生版本被用来检测精神疾病。自我完成工具被用来评估症状的严重程度，主观认知功能，工作和社会适应，耻辱，接受疾病和治疗satisfactions.esults：90名参与者包括23名妇女（26%），33（37%）已感染丙型肝炎医源性，42（47%）通过注射吸毒和其余（17%）的来源不明。抑郁症的1个月患病率为28%，其中72%以前未被诊断，焦虑症的患病率为24%，其中86%以前未被诊断。目前的美沙酮维持治疗与抑郁症的风险密切相关（比值比，5.0; 95%CI，1.08-23.0）。在调整年龄和性别后，抑郁症与较差的工作和社会适应、较低的疾病接受度、较高的疾病耻辱感、较差的思维和注意力以及较高的主观身体症状有关（所有P
Objective: We examined a group of patients awaiting interferon treatment for hepatitis C to estimate the prevalence and detection rates of and risk factors for mood disorders.Methods: The Structured Clinical Interview for DSM-IV Axis I Disorders: Clinician Version was used to detect psychiatric disorder. Self-completion instruments were used to rate symptom severity, subjective cognitive function, work and social adjustment, stigma, acceptance of illness and treatment satisfaction.esults: The 90 participants included 23 women (26%); 33 (37%) had contracted hepatitis C iatrogenically, 42 (47%) through injecting drug use and the remainder (17%) were of unknown origin. There was a 28% 1 -month prevalence of depressive disorders, 72% of whom were previously undiagnosed, and a 24% prevalence of anxiety disorders, 86% previously undiagnosed. Current methadone maintenance was strongly associated with risk of depression (odds ratio, 5.0; 95% CI, 1.08-23.0). After adjustment for age and sex, depression was associated with poorer work and social adjustment, lower acceptance of illness, higher illness stigma, poorer reported thinking and concentration, and higher levels of subjective physical symptoms (all P