Imaging of atherosclerotic cardiovascular disease
Imaging of atherosclerotic cardiovascular disease
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DOI：
10.1038/nature06803
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发表时间：
2008-02-21
期刊：
影响因子：
64.8
通讯作者：
Fayad, Zahi A.
中科院分区：
文献类型：
--
作者：
Sanz, Javier;Fayad, Zahi A.
动脉粥样硬化的特征是动脉壁增厚，这是一个缓慢而“安静”地发生数十年的过程。这种延长的病程为症状发生前的诊断提供了机会。但是，直到最近，只能观察到晚期动脉粥样硬化疾病。现在，成像技术的发展提供了许多诱人的前景，包括早期检测动脉粥样硬化，根据出现动脉粥样硬化症状的概率对个体进行分组，评估治疗结果以及提高目前对动脉粥样硬化生物学的理解。
Atherosclerosis is characterized by thickening of the walls of the arteries, a process that occurs slowly and 'silently' over decades. This prolonged course of disease provides a window of opportunity for diagnosis before symptoms occur. But, until recently, only advanced atherosclerotic disease could be observed. Now, developments in imaging technology offer many enticing prospects, including detecting atherosclerosis early, grouping individuals by the probability that they will develop symptoms of atherosclerosis, assessing the results of treatment and improving the current understanding of the biology of atherosclerosis.