Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: a cross-sectional study.
Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: a cross-sectional study.
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DOI：
10.1186/1756-0500-7-394
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发表时间：
2014-06-25
影响因子：
1.8
通讯作者：
Ndumbe PM
中科院分区：
文献类型：
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作者：
Frambo AA;Atashili J;Fon PN;Ndumbe PM
虽然感染B型肝炎病毒（HBV）仍然是一个全球性的公共卫生问题，很少有人知道它的流行病学在非洲撒哈拉以南地区怀孕。本研究旨在确定喀麦隆农村布埃亚卫生区（BHD）孕妇中乙型肝炎B表面抗原（HBsAg）阳性的患病率，并确定相关因素。我们还评估了孕妇对B型肝炎的知识。进行了一项横断面描述性研究。使用结构化问卷和临床检查对参与者进行评估，然后使用商业快速诊断测试对HBsAg进行筛查。使用B型肝炎基础知识汇总评分进行知识评估。在研究的176名孕妇中，9.7%（95% CI：5.7%，15%）的HBsAg检测结果呈阳性。评估的风险因素均与HBsAg阳性无显著相关性。B型肝炎知识总分范围为0 - 12，平均值为1.5（SD = 3.14，中位数= 0，IQR = 0 - 0）。只有16%的参与者得分超过6/12。参与者的知识总结得分与教育水平相关（p值= 0.0037）。HBsAg在育龄妇女中的高流行率（9.7%）表明HBV的垂直传播可能是布埃亚卫生区的一个公共卫生问题。孕妇对乙肝病毒的认知程度较低。我们建议所有孕妇都应该进行乙肝病毒的常规筛查，并应向孕妇提供有关乙肝病毒的健康教育，特别是在产前检查期间。
Although infection with Hepatitis B Virus (HBV) remains a global public health problem, little is known about its epidemiology in pregnancy in sub-Saharan Africa. This study sought to determine the prevalence of, and identify factors associated with hepatitis B surface antigen (HBsAg) positivity among pregnant women in the Buea Health District (BHD) in rural Cameroon. We also assessed pregnant women’s knowledge about hepatitis B. A cross-sectional, descriptive study was undertaken. Participants were evaluated using a structured questionnaire with clinical examination and were then screened for HBsAg using a commercial rapid diagnostic test. Assessment of knowledge was done using a hepatitis B basic knowledge summary score. Of the 176 pregnant women studied, 9.7% (95% CI: 5.7%, 15%) tested positive for HBsAg. None of the risk factors assessed was significantly associated with HBsAg positivity. The hepatitis B knowledge summary score ranged from 0 to 12 with a mean of 1.5 (SD = 3.14, median = 0, IQR = 0 to 0). Only 16% of participants had scores greater than 6/12. The knowledge summary score of the participants was associated with the educational level (p-value = 0.0037). The high prevalence of HBsAg (9.7%) among women of child bearing age suggests that vertical transmission of HBV may be a public health problem in Buea Health District. Knowledge of HBV among pregnant women was poor. We recommend that all pregnant women ought to be routinely screened for HBV and that health education on HBV should be provided to pregnant women especially during antenatal visits.