Outbreak of contact lens-related Fusarium keratitis in France
Outbreak of contact lens-related Fusarium keratitis in France
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DOI：
10.1097/ico.0b013e318173144d
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发表时间：
2008-10-01
期刊：
影响因子：
2.8
通讯作者：
Borderie, Vincent M.
中科院分区：
文献类型：
--
作者：
Gaujoux, Thomas;Chatel, Marc Antoine;Borderie, Vincent M.
背景/目的：在最近新加坡和美国发生的一系列镰刀菌角膜炎病例的背景下。我们描述了真菌性角膜炎的爆发，镰刀菌属之间，接触透镜配戴者生病法国。回顾了2004年1月至2006年11月在巴黎国家眼科中心医院眼科诊断的所有镰刀菌角膜炎病例。进行了标准化的电话采访，以获得更多的临床信息的研究和危险因素的分析。结果：在研究期间，17例患者（18患眼）被诊断为镰刀菌角膜炎。绝大多数（14例患者，82%）配戴角膜接触镜。6例患者（43%的角膜接触透镜配戴者）报告使用R和MoistureLoc。8例患者报告使用其他品牌的接触透镜清洁SOIL 16011。最终最佳矫正视力在20/20 ~光感之间。5例（29.5%）需急诊治疗性或结构性角膜移植。没有具体的差异，包括镰刀菌物种或严重程度的角膜炎之间的角膜炎与ReNu MoistureLoc和角膜炎没有ReNu MoistureLoc.Conclusions：这一系列报道的第一次爆发镰刀菌角膜炎在欧洲。再一次，ReNu与MoistureLoc，一种多功能透镜消毒液与镰刀菌角膜炎有关。
Background/Aims: In the context of a recent series of Fusarium keratitis cases in Singapore and the United States. we describe an outbreak of fungal keratitis attributable to Fusarium species among, contact lens wearers ill France.Methods: Hospital-based case series. All cases of Fusarium keratitis diagnosed in Department of Ophthalmology of the Centre Hospitalier National d'Ophtalmologic des Quinze-Vingts in Paris were reviewed front January 2004 through November 2006. A standardized telephone interview was conducted to obtain additional clinical information for research and the analysis of risk factors.Results: During the study period, 17 Patients (18 affected eyes) were diagnosed with Fusarium keratitis. The vast majority (14 Patients, 82%) wore contact lenses. Six patients (43% of contact lens wearers) reported using R with MoistureLoc. Eight patients reported using others brands of contact lens cleaning SOIL16011. The final best corrected visual acuity ranged front 20/20 to light perception 5 Patients (29.5%) required emergency therapeutic or tectonic corneal transplantation. No specific differences including Fusarium species or severity of keratitis were found between keratitis with ReNu MoistureLoc and keratitis without ReNu MoistureLoc.Conclusions: This series reports the first outbreak of Fusarium keratitis in Europe. Once again, ReNu with MoistureLoc, a multipurpose lens disinfecting solution to be related with Fusarim keratitis.