CLINICAL STUDY OF OXYGEN TENSION OF URINE + RENAL STRUCTURES 2

CLINICAL STUDY OF OXYGEN TENSION OF URINE + RENAL STRUCTURES 2
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DOI:
10.1016/s0022-5347(17)63916-8
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发表时间:
1964-01-01
期刊:
影响因子:
6.6
通讯作者:
LEONHARDT, KO
LEONHARDT, KO
中科院分区:
医学1区
文献类型:
--
作者:
LANDES, RR;DURUMAN, N;LEONHARDT, KO

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实际上,肾皮质和肾髓质是由不同的循环系统供应血液的,它们在五个方面彼此不同:1)皮质循环是一个高压、高速系统,60 mm Hg。在肾小球和2.5秒。皮层毛细血管的循环时间延髓循环是一个低压、低速系统,15毫米汞柱。50秒循环时间2)灌注皮质的血液是灌注髓质的10 ~ 20倍,而灌注髓质深部的血液不到2%。3)可能存在一个功能性的动静脉分流机制,允许大量的高氧合后肾小球血液进入小叶间静脉,而不穿过肾小管周围毛细血管。在延髓中几乎没有分流。
In effect, the renal cortex and medulla are supplied by separate circulations, which differ from each other in five respects: 1) The cortical circulation is a high-pressure, high-velocity system, 60 mm. Hg. at the glomerulus and 2.5 sec. circulation time through the cortical capillaries. The medullary circulation is a low-pressure, low-velocity system, 15 mm. Hg. and 50 sec. circulation tirn. e through the vasa recta.2) Ten to twenty times as much blood perfuses the cortex as the medulla and less than 2 per cent perfuses the deep medulla. 3) There probably exists a functional arteriovenous shunting mechanism in the cortex permitting large quantities of highly oxygenated post-glomerular blood to find access to the interlobular veins without traversing the peritubular capillaries. Little if any shunting occurs in the n, edulla.