Clenbuterol and anabolic steroids: A previously unreported cause of myocardial infarction with normal coronary arteriograms
Clenbuterol and anabolic steroids: A previously unreported cause of myocardial infarction with normal coronary arteriograms
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DOI：
10.1097/00007611-199808000-00019
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发表时间：
1998-08-01
影响因子：
1.1
通讯作者：
Plumb, VJ
中科院分区：
文献类型：
--
作者：
Goldstein, DR;Dobbs, T;Plumb, VJ
在过去10年中，报告了几例与使用合成代谢类固醇相关的心肌梗死病例。解释这种关联的假定机制包括脂质水平、纤溶系统和血小板聚集的变化。盐酸克伦特罗是一个Pn-激动剂与合成代谢的属性，以前没有见过，VITH心肌梗死，我们报告的情况下，心肌梗死在其他健康的26岁的健美运动员谁最近使用盐酸克伦特罗和合成代谢类固醇.在这种情况下，两种药物的协同作用似乎在梗塞中起了作用，在任何抗凝剂或溶栓治疗之前的正常冠状动脉造影强烈表明冠状动脉痉挛是梗塞的机制，
During the last 10 years, several cases of myocardial infarction associated with anabolic steroid use have been reported. Postulated mechanisms to explain this association have included changes in lipid levels, the fibrinolytic system, and platelet aggregation. Clenbuterol is a Pn-agonist with anabolic properties that has not been seen previously,vith myocardial infarction, We report a case of myocardial infarction in an otherwise healthy 26-year-old body-builder who recently used clenbuterol and anabolic steroids. In this case, synergistic effects of the two agents seem likely to have played a role in the infarct, The normal coronary arteriograms before any anticoagulant or thrombolytic therapy strongly suggest coronary spasm as the mechanism of the infarct,