Combining Spatial Registration With Clutter Filtering for Power-Doppler Imaging in Peripheral Perfusion Applications.
Combining Spatial Registration With Clutter Filtering for Power-Doppler Imaging in Peripheral Perfusion Applications.
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DOI：
10.1109/tuffc.2022.3211469
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发表时间：
2022-12
影响因子：
3.6
通讯作者：
Abbey, Craig K. K.
中科院分区：
文献类型：
--
作者：
Insana, Michael F. F.;Dai, Bingze;Babaei, Somaye;Abbey, Craig K. K.
关键词：
能量多普勒超声（PD-US）成像对微血管系统中血细胞运动的回声敏感，但由于难以过滤非血液回声源，因此通常无特异性。我们正在研究在没有造影剂的情况下使用PD-US成像进行外周血灌注常规评估的可能性。开发的策略是基于实验验证的组织灌注的计算模型，模拟典型的体内条件。该模型认为，在一个领域的移动杂波和噪声的定向和扩散的血液灌注状态。应用空间配准方法以在杂波和噪声滤波之前使组织运动最小化。结果表明，该方法有效地抑制了面内杂波运动。虽然平面外运动仍然是杂波滤波器泄漏的一个强有力的来源，这些配准误差很容易通过直接修改扫描技术和空间平均来最小化。
Power-Doppler ultrasonic (PD-US) imaging is sensitive to echoes from blood cell motion in the microvasculature but generally nonspecific because of difficulties with filtering nonblood-echo sources. We are studying the potential for using PD-US imaging for routine assessments of peripheral blood perfusion without contrast media. The strategy developed is based on an experimentally verified computational model of tissue perfusion that simulates typical in vivo conditions. The model considers directed and diffuse blood perfusion states in a field of moving clutter and noise. A spatial registration method is applied to minimize tissue motion prior to clutter and noise filtering. The results show that in-plane clutter motion is effectively minimized. While out-of-plane motion remains a strong source of clutter-filter leakage, those registration errors are readily minimized by straightforward modification of scanning techniques and spatial averaging.