Wrapping of nanoparticles by membranes
Wrapping of nanoparticles by membranes
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DOI：
10.1016/j.cis.2014.02.012
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发表时间：
2014-06-01
影响因子：
15.6
通讯作者：
Weikl, Thomas R.
中科院分区：
文献类型：
--
作者：
Bahrami, Arnir H.;Raatz, Michael;Weikl, Thomas R.
纳米粒子如何与生物膜相互作用是理解其生物活性的核心。如果纳米颗粒和膜之间的粘附相互作用足够强以补偿膜弯曲的成本，则生物膜包裹纳米颗粒。在这篇文章中，我们回顾了最近的结果，从理论和模拟，提供了新的见解的相互作用的弯曲和粘附能量的纳米粒子的包裹膜。这些结果表明，弯曲和粘附在包裹过程中的相互作用的强烈影响的颗粒-膜粘附电位的相互作用范围，由纳米颗粒的形状，并通过在包裹过程中的膜囊泡的形状变化。粒子-膜粘附势的相互作用范围对于单个纳米粒子的包裹过程和膜小管对纳米粒子的协同包裹都是至关重要的。(C)© 2014 Elsevier B. V.保留所有权利。
How nanoparticles interact with biomembranes is central for understanding their bioactivity. Biomembranes wrap around-nanoparticles if the adhesive interaction between the nanoparticles and membranes is sufficiently strong to compensate for the cost of membrane bending. In this article, we review recent results from theory and simulations that provide new insights on the interplay of bending and adhesion energies during the wrapping of nanoparticles by membranes. These results indicate that the interplay of bending and adhesion during wrapping is strongly affected by the interaction range of the particle-membrane adhesion potential, by the shape of the nanoparticles, and by shape changes of membrane vesicles during wrapping. The interaction range of the particle-membrane adhesion potential is crucial both for the wrapping process of single nanoparticles and the cooperative wrapping of nanoparticles by membrane tubules. (C) 2014 Elsevier B.V. All rights reserved.