Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations.
Calculation of Organ Doses for a Large Number of Patients Undergoing CT Examinations.
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DOI：
10.2214/ajr.14.14135
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发表时间：
2015-10
期刊：
影响因子：
--
通讯作者：
Lee C
中科院分区：
文献类型：
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作者：
Bahadori A;Miglioretti D;Kruger R;Flynn M;Weinmann S;Smith-Bindman R;Lee C
开发并证明一种自动计算方法，为接受CT检查的大型儿科和成人患者队列提供器官剂量评估。我们采用了先前发表的两个剂量库：CTDIvol标准化的器官剂量库和mAs标准化的CTDIw库。我们开发了一种算法，使用两个剂量库和DICOM数据中的CT扫描参数计算器官剂量。为了证明已建立的方法，我们计算了从美国四个医疗保健系统中随机选择的儿科（n=2499）和成人（n=2043）CT扫描的器官剂量，并将成人器官剂量与ImPACT计算器计算的值进行了比较。中位脑剂量为20 mGy（儿童）和24 mGy（成人），11%（儿童）和18%（成人）的头部扫描的脑剂量大于40 mGy。NCI和ImPACT方法均为所有器官提供了相似的器官剂量（中位数差异< 20%），但靠近扫描边界的器官除外。扫描覆盖范围和体模解剖结构的视觉比较显示，与ImPACT方法相比，基于NCI方法的真实计算体模提供了更真实的器官剂量。本研究开发的自动器官剂量计算方法减少了计算大量患者剂量所需的时间。我们已经成功地利用这种方法进行了各种CT相关的研究，包括回顾性流行病学研究和CT剂量趋势分析研究。
To develop and demonstrate an automated calculation method to provide organ dose assessment for a large cohort of pediatric and adult patients undergoing CT examinations. We adopted two dose libraries that were previously published: the CTDIvol-normalized organ dose library and the mAs-normalized CTDIw library. We developed an algorithm to calculate organ doses using the two dose libraries and CT scan parameters available from DICOM data. To demonstrate the established method, we calculated organ doses for pediatric (n=2499) and adult (n=2043) CT scans randomly selected from four health care systems in the United States, and compared the adult organ doses with the values calculated from the ImPACT calculator. Median brain dose was 20 mGy (pediatric) and 24 mGy (adult), and brain dose was greater than 40 mGy for 11% (pediatric) and 18% (adult) of head scans. Both the NCI and the ImPACT methods provided similar organ doses (median discrepancy < 20%) for all organs except for the organs located close to scan boundaries. The visual comparisons of scan coverage and phantom anatomies revealed that the NCI method based realistic computational phantoms provides more realistic organ doses compared to the ImPACT method. The automated organ dose calculation method developed in this study reduces the time needed to calculate doses on a large number of patients. We have successfully utilized this method for a variety of CT-related studies including retrospective epidemiological study and CT dose trend analysis studies.