A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype.
A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype.
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DOI:
10.1093/bioinformatics/btp121
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发表时间:
2009-05-01
期刊:
影响因子:
--
通讯作者:
Moslehi R
中科院分区:
文献类型:
--
作者:
Kuznetsov IB;McDuffie M;Moslehi R
Summary:N-acetyltransferase-2 (NAT2) is an important enzyme that catalyzes the acetylation of aromatic and heterocyclic amine carcinogens. Individuals in human populations are divided into three NAT2 acetylator phenotypes: slow, rapid and intermediate. NAT2PRED is a web server that implements a supervised pattern recognition method to infer NAT2 phenotype from SNPs found in NAT2 gene positions 282, 341, 481, 590, 803 and 857. The web server can be used for a fast determination of NAT2 phenotypes in genetic screens. Availability:Freely available at http://nat2pred.rit.albany.edu Contact:ikuznetsov@albany.edu; rmoslehi@albany.edu Supplementary information:Supplementary data are available at Bioinformatics online.
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影响因子:
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通讯作者:
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BLUM, M;GRANT, DM;MEYER, UA
通讯作者:
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Donnelly, P
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