Identification of the reoasting reaction products of ferulic and sinapic acids and their xanthine oxidase inhibitory activity
Identification of the reoasting reaction products of ferulic and sinapic acids and their xanthine oxidase inhibitory activity
复制标题
阿魏酸和芥子酸复烤反应产物的鉴定及其黄嘌呤氧化酶抑制活性
DOI：
10.1093/bbb/zbac173
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Toshiya Masuda
中科院分区：
文献类型：
--
作者：
Yukino Shindo;Asuka Taniguchi;Akiko Masuda;Toshiya Masuda
采用高效液相色谱法对阿魏酸和辛酸的焙烧反应产物进行了分析，并对其成分进行了分离。结构分析表明，主要化合物为相应的4-乙烯基酚的低聚物。对分离得到的化合物进行了黄嘌呤氧化酶（XO）抑制活性测定。观察到阿魏酸的一些低聚物具有中等的XO抑制活性。
The roasting reaction products of ferulic and sinapic acids were analyzed using high-performance liquid chromatography (HPLC) and their constituent compounds were isolated. Structural analysis revealed that the major compounds were oligomers of the corresponding 4-vinylphenols. The xanthine oxidase (XO) inhibitory activity of the isolated compounds was also measured. Moderate XO inhibitory activity of some oligomers afforded from ferulic acid was observed.