Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding
Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding
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DOI：
10.1039/c8cc08657e
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发表时间：
2019-01-18
影响因子：
4.9
通讯作者：
Muraoka, Takahiro
中科院分区：
文献类型：
--
作者：
Okada, Shunsuke;Matsusaki, Motonori;Muraoka, Takahiro
Coupling of thiol and urea-type -NHC(=X)NH2 (X = O or NH) groups is effective in promoting oxidative protein folding. In particular, a thiol compound coupled with a guanidyl (X = NH) group significantly accelerates the rates of folding processes and enhances the yields of native proteins.
