Effects of cigarette smoking on rhinologic diseases: Korean National Health and Nutrition Examination Survey 2008-2011
Effects of cigarette smoking on rhinologic diseases: Korean National Health and Nutrition Examination Survey 2008-2011
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DOI：
10.1002/alr.21553
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发表时间：
2015-10-01
影响因子：
6.4
通讯作者：
Kim, Jeong-Whun
中科院分区：
文献类型：
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作者：
Lee, Woo Hyun;Hong, Seung-No;Kim, Jeong-Whun
背景几项研究表明，在大量的亚洲人群中，吸烟与一般性鼻部疾病之间存在关系。目前的研究进行，以更好地了解香烟烟雾暴露对神经系统疾病的影响，在韩国人.MethodsData从2008-2011年韩国国家健康和营养检查调查，在韩国的非制度化人口的横断面调查。在接受调查的37，753人中，有11，589名成年参与者完成了关于肾脏病症状和吸烟行为的问卷，接受了鼻内窥镜检查，并提供了尿液收集。在这项研究中调查的鼻科疾病包括主观嗅觉功能障碍，鼻炎症状，慢性鼻窦炎（CRS），鼻中隔偏曲和阻塞性症状。疾病和吸烟之间的关系进行了评估，采用多元回归analysis.ResultsIn韩国，加权患病率的主观嗅觉功能障碍，鼻炎症状，CRS，鼻中隔偏曲与阻塞性症状分别为4.6%，27.2%，6.2%和4.0%。在调整年龄、性别、居住地、家庭收入、教育和职业后，与主动吸烟显著相关的唯一疾病是40岁及以上参与者的CRS（调整后的比值比= 1.427，95%置信区间= 1.050至1.938）。对于积极吸烟的每一年，CRS患病率增加1.5%。没有一个神经系统疾病检查与被动吸烟。ConclusionOur研究表明，CRS似乎与主动吸烟的老年参与者。鉴于韩国CRS的患病率相对较高，需要对其相关性和预防进行进一步的纵向研究。
BackgroundSeveral studies have shown a relationship between cigarette smoking and general diseases of the nose in a large Asian population. The current study was conducted to better understand the effect of cigarette smoke exposure on rhinologic diseases in Koreans.MethodsData were obtained from the 2008-2011 Korea National Health and Nutrition Examination Survey, a cross-sectional survey of the noninstitutionalized population in Korea. Of the 37,753 people surveyed, 11,589 adult participants had completed questionnaires on rhinologic symptoms and smoking behaviors, had undergone nasal endoscopy, and had provided urine collection were enrolled. Rhinologic diseases investigated in this study included subjective olfactory dysfunction, rhinitis symptoms, chronic rhinosinusitis (CRS), and nasal septal deviation with obstructive symptoms. The relationship between disease and cigarette smoking was evaluated using multivariate regression analyses.ResultsIn South Korea, the weighted prevalence of subjective olfactory dysfunction, rhinitis symptoms, CRS, and nasal septal deviation with obstructive symptoms was 4.6%, 27.2%, 6.2%, and 4.0%, respectively. The only disease significantly associated with active smoking was CRS in participants 40 years of age and older after adjusting for age, sex, residency, house income, education, and occupation (adjusted odds ratio = 1.427, 95% confidence interval = 1.050 to 1.938). For each year of active smoking, CRS prevalence increased by 1.5%. None of the rhinologic diseases examined were associated with passive smoking.ConclusionOur study showed that CRS seems to be associated with active smoking in older participants. Considering the relatively high prevalence of CRS in Korea, further longitudinal researches for their association and prevention are required.