The neural correlates of sign versus word production
The neural correlates of sign versus word production
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DOI：
10.1016/j.neuroimage.2007.02.040
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发表时间：
2007-05-15
期刊：
影响因子：
5.7
通讯作者：
Grabowski, Thomas J.
中科院分区：
文献类型：
--
作者：
Emmorey, Karen;Mehta, Sonya;Grabowski, Thomas J.
手语的产生涉及到两个大的关节(手)在空间中移动并接触身体。相比之下，语音产生需要舌头和声道的微小运动，没有明显的空间对比。尽管如此，这两种语言类型都表现出具有相似属性(例如，片段、音节、特征层次)的次词汇结构层。为了探讨哪些神经区参与了非情态语言的产生，以及哪些神经元与手语和口语的输入输出机制有关，我们重新分析了29名聋人手语和听力说话者的正电子发射计算机断层扫描数据，他们参与了一系列单独的研究。参与者被要求用美国手语(ASL)或英语公开地说出不同语义类别的具体物体的名字。基线任务要求参与者判断未知面孔的方位(公开回答“是”/“否”表示直立/倒立)。随机效应分析表明，左侧内侧颞叶皮质和左侧额叶下回同样参与语音和手势的产生，这表明这些区域在词汇获取中起着不依赖于通道的作用。在左侧顶叶内，有两个区域的信号比语音更活跃：边缘上回(峰值坐标：-60，-35，+27)和顶上小叶(峰值坐标：-26，-51，+54)。这些区域的激活可能与手语的特定通道输出参数有关。具体地说，左SMG内的激活可能反映了ASL中语音加工的各个方面(例如，手形的选择和发音特征的位置)，而SPL内的激活可能反映了对运动输出的本体感觉监测。(C)2007 Elsevier Inc.保留所有权利。
The production of sign language involves two large articulators (the hands) moving through space and contacting the body. In contrast, speech production requires small movements of the tongue and vocal tract with no observable spatial contrasts. Nonetheless, both language types exhibit a sublexical layer of structure with similar properties (e.g., segments, syllables, feature hierarchies). To investigate which neural areas are involved in modality-independent language production and which are tied specifically to the input-output mechanisms of signed and spoken language, we reanalyzed PET data collected from 29 deaf signers and 64 hearing speakers who participated in a series of separate studies. Participants were asked to overtly name concrete objects from distinct semantic categories in either American Sign Language (ASL) or in English. The baseline task required participants to judge the orientation of unknown faces (overtly responding 'yes'/,no' for upright/inverted). A random effects analysis revealed that left mesial temporal cortex and the left inferior frontal gyrus were equally involved in both speech and sign production, suggesting a modality-independent role for these regions in lexical access. Within the left parietal lobe, two regions were more active for sign than for speech: the supramarginal gyros (peak coordinates: -60, -35, +27) and the superior parietal lobule (peak coordinates: -26, -51, +54). Activation in these regions may be linked to modality -specific output parameters of sign language. Specifically, activation within left SMG may reflect aspects of phonological processing in ASL (e.g., selection of hand configuration and place of articulation features), whereas activation within SPL may reflect proprioceptive monitoring of motoric output. (C) 2007 Elsevier Inc. All rights reserved.