Q-FEVER IN THE GREEK ISLAND OF CRETE - EPIDEMIOLOGIC, CLINICAL, AND THERAPEUTIC DATA FROM 98 CASES
Q-FEVER IN THE GREEK ISLAND OF CRETE - EPIDEMIOLOGIC, CLINICAL, AND THERAPEUTIC DATA FROM 98 CASES
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DOI：
10.1093/clinids/20.5.1311
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发表时间：
1995-05-01
影响因子：
11.8
通讯作者：
TSAPARAS, N
中科院分区：
文献类型：
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作者：
TSELENTIS, Y;GIKAS, A;TSAPARAS, N
对希腊克里特岛Q热的流行病学、临床和治疗进行了回顾性研究。在5年间(-1993年)，共检查了1,298例患者，确诊98例。年龄在20-29岁和30-39岁的人似乎有更高的感染风险，接触动物被发现是感染Q热的主要危险因素。感染的主要临床表现为发热(91.7%)和呼吸系统疾病(88.5%)，而肝炎仅占少数(7.1%)，胸片常见肺间质改变(36.4%)和肺泡改变(34.4%)，超声心动图也有异常表现，无论是否接受四环素或红霉素治疗，患者的发热持续时间没有差异，这可能是四环素治疗延迟的原因。
A retrospective study was undertaken in Crete, Greece, to investigate the epidemiologic, clinical, and therapeutic aspects of Q fever, Over a period of 5 years (1989-1993), 1,298 patients were examined and 98 cases were identified. Individuals who were aged 20-29 years and 30-39 years appeared to have an increased risk of infection, Contact with animals was found to be a major risk factor for acquisition of Q fever. The predominant clinical manifestations of the infection were fever (91.7% of patients) and respiratory disease (88.5%), whereas hepatitis was the dominant feature in only a minority (7.1%) of patients, Chest radiographs frequently revealed pulmonary interstitial changes (36.4% of patients) and alveolar changes (34.4%), Abnormal echocardiographic findings were also observed, There was no difference in the duration of fever whether the patient received therapy with tetracycline or erythromycin, a finding that may be explained by the delay in initiating tetracycline therapy.